BACKGROUND The neural constraints underlying hemiparetic gait dysfunction are associated with abnormal kinetic outflow and altered muscle synergy structure. Recent evidence from our lab implicates the lesioned hemisphere in mediating the expression of abnormally coupled hip adduction and knee extension synergy, suggesting a role of cortical networks in the regulation of lower limb motor outflow...

Studies have reported the importance of mitochondria in sperm functionality. However, for some species, the glycolytic pathway appears to be as important as oxidative phosphorylation in ATP synthesis and sperm kinetics. These mechanisms have not been fully elucidated for bovine spermatozoa. Therefore, the aim of this study was to evaluate the role of mitochondria and the glycolytic pathway in A...

Activated DNA-directed DNA synthesis catalyzed by Rauscher leukemia virus (RLV) and other type C mammalian retroviral DNA polymerases is uniquely stimulated by biologically active polyamines. Cationic trypanocides may act as antagonists of polyamine function. As described here, several cationic trypanocides stimulate RLV polymerase-catalyzed DNA-directed DNA synthesis at concentrations signific...

The regulation of platelet adenylate cyclase by free metal and metal-ATP was studied. The effects on that regulation of adenosine, under stimulatory or inhibitory conditions, and of prostaglandin El, were evaluated. Under conditions when CAMP formation was linear with respect to time and protein concentration, double reciprocal plots with respect to either free (excess) Mg+ or MgATP were linear...

N-Methyl-D-Aspartate receptors (NMDARs) play important physiological as well as pathological roles in the central nervous system (CNS). While NMDAR competitive antagonists, such as D-2-Amino-5-Phosphopentanoic acid (AP5) have been shown to impair learning and memory, the non-competitive antagonist, memantine, is paradoxically beneficial in mild to moderate Alzheimer's disease (AD) patients. It ...

Purpose: Low birth weight (LBW) is one of the most serious health problems in infants. Many studies indicate that LBW infants, who survive, may suffer from long- and short-term physical,mental, and social problems. This study aimed to determine the effect of massage therapy on weight gain of LBW neonates. Methods: This study was a randomized clinical trial. A total of 45 LBW neonates were rand...

Pulsed electromagnetic fields (PEMFs) are used as non-invasive tools to enhance microcirculation and tissue oxygenation, with a modulatory influence on the microvasculature. This study aimed measure acute effect of PEMF muscle oxygenation its pulmonary oxygen kinetics during exercise. Eighteen male cyclists performed, different days, constant-load exercise in both active (ON) inactive (OFF) sti...