Objective: To investigate the effect and clinical significance of myeloid-derived suppressor cells (MDSCs) levels serum miRNA-21 expression in advanced non-small cell lung cancer (NSCLC) patients. Methods: Advanced NSCLC patients treated at First People’s Hospital Tongxiang City, Zhejiang Province, between July 2021 June 2022 were included this study. MDSCs peripheral circulation assessed by fl...

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and the proliferating antigen Ki67 have been widely studied in several tumors. However, their role as indicator in non-small cell lung cancer (NSCLC) remains unknown. Here, we investigated the expression of PTEN and Ki67 in NSCLC tissues and paired normal lung tissues to identify whether these proteins are associated with lung cance...

The cell cycle of antigen-specific T cells in vivo has been examined by using a few methods, all which possess some limitations. Bromodeoxyuridine (BrdU) marks that are or recently completed S-phase, and carboxyfluorescein succinimidyl ester (CFSE) detects daughter after division. However, these dyes do not allow identification the phase at time analysis. An alternative approach is to exploit K...

Background : Basal cell carcinoma (BCC) is the most commonest malignant tumor of skin especially fair-skinned individuals makes up roughly 70–80% all tumors. In certainty, this malignancy had a variety many sub-types, through distinct histo-morphological appearance and biological function. Unlike other tumors, usually has an affirmative clinical course, developing slowly just locally. Antibodie...

There is no satisfactory biomarker yet available for predicting the likelihood of premalignant changes or carcinoma developing in Barrett's or columnar lined oesophagus. In this study we have evaluated the proliferation of squamous epithelium, columnar epithelium from columnar lined oesophagus and gastric columnar epithelium from 23 Barrett's patients using positive immunoreactivity with the mo...

There is no satisfactory biomarker yet available for predicting the likelihood of premalignant changes or carcinoma developing in Barrett's or columnar lined oesophagus. In this study we have evaluated the proliferation of squamous epithelium, columnar epithelium from columnar lined oesophagus and gastric columnar epithelium from 23 Barrett's patients using positive immunoreactivity with the mo...