background: antiself humoral immune responses have been detected not only in classical autoimmune dis­eases, but autoantibodies have also been found in sera of patients suffering from chronic parasitic dis­eases. we aimed to investigate the role of fasciolosis as a trigger factor of autoimmune reactivity by searching some anti­bodies related to hepatobiliary systems, in patients with fasciolosi...

Background: Fasciolosis is a crucial helminthes disease caused by two trematodes of the genus Fasciola: Fasciola hepatica (temperate liver fluke) and gigantica (tropical fluke). Methods: A cross-sectional study was conducted on cattle sheep in slaughterhouse to detect animals infected with Fasciolosis. Liver samples were collected from transferred laboratory for histopathological immunohistoche...

Fasciolosis is a disease caused by liver fluck of the genus of Fasciola. Diagnosis of fasciolosis has been challenging for a long period due to low sensitivity of the coprological diagnostic method. In this study, an in-house Dot-ELISA method; using excretion-secretory (ES Ag) and Crude (Cr Ag) antigens of Fasciola was described for diagnosis of fasciolosis in cattle. For this purpose, the sera...

Parasitic diseases are huge problem for human and veterinary medicine and for economy, agriculture and wildlife management. One of these diseases is fasciolosis, which is caused by two trematode species, Fasciola hepatica (liver fluke) and Fasciola gigantica. Only F. hepatica is a concern in Europe and Americas but the distribution of both species overlaps in many areas of Africa and Asia (Mas-...

Fasciolosis is the burning problem of the livestock rearing community having huge morbidity, mortality, and economic losses to livestock industries in our country Pakistan. The faecal and liver biopsy samplings were examined by polymerase chain reaction (PCR) and microscopy technique during the entire study. A total of 307 samples including 149 samples from Karak and 158 samples from Kohat abat...

Fasciolosis, a food-borne trematodiasis, results following infection with the parasites, Fasciola hepatica and Fasciola gigantica. These trematodes greatly affect the global agricultural community, infecting millions of ruminants worldwide and causing annual economic losses in excess of US $3 billion. Fasciolosis, an important zoonosis, is classified by WHO as a neglected tropical disease with ...

human fasciolosis is deemed as an emerging/re-emerging infection, hence making it an important human parasitic disease. in contrast to northern parts of iran, human cases of fasciolosis in southern iran are rare and sporadic. we report a sporadic case of fasciolosis in southern iran (fars province) who presented with prolonged fever. our report could suggest that there might be new foci emergin...

BACKGROUND Tropical fasciolosis caused by Fasciola gigantica infection is one of the major diseases infecting ruminants in the tropical regions of Africa and Asia including Thailand. Parasitological diagnosis of fasciolosis is often unreliable and possesses low sensitivity. Therefore, the detection of circulating parasite antigens is thought to be a better alternative for diagnosis of fasciolos...

Fasciolosis caused by Fasciola hepatica and Fasciola gigantica is one of the major public health problems in the world and in Iran. Considering that stool examination for Fasciola eggs is not a sensitive method and immunodiagnosis methods are more applicable for this purpose, so the present study was conducted to compare the somatic (S) and cysteine proteinase (CP) antigens of F. gigantica in I...

The effect of liver fluke infection (Fasciola hepatica) on ion transport in the rat proximal colon was evaluated with electrophysiological methods using an Ussing apparatus. Rats were orally infected with F. hepatica metacercariae. The experimental groups of rats at 4 weeks post-infection (wpi) were in the acute stage of fasciolosis, while those at 7, 10 and 13 wpi represented the chronic phase...