Candida africana was previously proposed as a new species within the Candida albicans species complex, together with C. albicans and C. dubliniensis, although further phylogenetic analyses better support its status as an unusual variant within C. albicans. Here we show that C. africana can be distinguished from C. albicans and C. dubliniensis by pyrosequencing of a short region of ITS2, and we ...

ABSTRACT: Candidiasis is a fungal infection caused by Candida albicans. Allium sativum (garlic) and Curcuma longa (turmeric) have been used as antifungal agents. The main aim of this study was to identify the effectiveness of these natural products towards C. albicans and on their pharmacological and toxicity aspects. Thus, agar disc diffusion method was used to study the antifungal activity of...

background: due to the predisposing conditions in patients with cystic fibrosis (cf) caused by defective mucociliary clearance facilitating colonization and invasion with candida species has dramatically increased. traditional methods for identifying problems are imminent and time-consuming. therefore, molecular techniques utilizing amplification of target dna provide quick and precise methods ...

although candida albicans is the most common etiologic agent of candidiasis, c. dubliniensis, has been emerged, as another pathogen resembles c. albicans in many phenotypic aspects and noted for its in vitro potential for fluconazole resistance. since there was no evidence of any report about detection of this organism in iran, this study was designed to use of five different tests for identifi...

Background: Candida albicans (C. albicans) may have cariogenic potential but its role in caries etiology has not been established. The aim of this study was to determine C. albicans in supragingival dental plaque and infected dentine of cervical and proximal in early childhood caries (ECC). Methods: This cross-sectional study was carried out on 6o children aged 2-5 years, which were divided int...

Normal rabbit alveolar macrophages were infected in vitro with Candida albicans. Early after infection, germ tube formation of phagocytized C. albicans was inhibited in contrast to extracellular (nonphagocytized) C. albicans. Over and 8-h period, plate counts of C. albicans incubated with alveolar macrophages revealed a decrease in colony-forming units in contrast to C. albicans alone. In addit...

background: the leaves of eucalyptus globulus (eucalyptus) are used for treatment of diabetes mellitus in traditional medicine. the aim of this study was to evaluate the effects of eucalyptus in treatment of established systemic infection with candida albicans in normal and streptozotocin-induced diabetic rats. methods: sixty normoglycemic male wistar rats, weighing 200-250 g, were selected and...

PURPOSE Candida albicans is an opportunistic pathogen that is commonly found in human microflora. Biofilm formation (BF) is known as a major virulence factor of C. albicans. The aim of this study was to examine the influence of bacterial presence on biofilm formation of C. albicans. MATERIALS AND METHODS The BF of Candida was investigated when it was co-cultured with C. albicans (C. albicans ...

OBJECTIVE To define the differences in antibiotics exposure, risk factors, and outcome in hospitalized patients with Candida albicans (C. albicans) and non-C. albicans candidemia. METHODS This is a multi-center retrospective study of 132 patients with candidemia from 5 tertiary-care educational hospitals in Shandong, China conducted between January 2009 and June 2010. Fifty-six of 132 (42.4%)...

Pathogenic mechanisms of Candida glabrata in oral candidiasis, especially because of its inability to form hyphae, are understudied. Since both Candida albicans and C. glabrata are frequently co-isolated in oropharyngeal candidiasis (OPC), we examined their co-adhesion in vitro and observed adhesion of C. glabrata only to C. albicans hyphae microscopically. Mice were infected sublingually with ...