Synergistic antibacterial interaction between Melissa officinalis extracts and antibioticsOlgica Stefanovic, Ljiljana Comic

The Effect of Melissa officinalis Extract on Streptozotocin-Induced Diabetes in Rats: A Stereological Study Pancreatic Islets and Beta-cells

The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained rosmarinic acid, including food-effects in healthy individuals. A total of eleven healthy individuals were randomly assigned to treatment arms in the two studies [Study 1 (fasted state) and Study 2 (fed state)]. Rosmarinic acid in serum was measured b...

Botanicals are an alternative option to prescription drugs for the alleviation of symptoms due to anxiety disorders and insomnia. Melissa officinalis L. has been shown as an anti-stress and anxiolytic agent. We previously reported moderate stress improvement in mice in which Cyracos(®), a standardized Melissa officinalis L. extract, was administrated. Cyracos(®) contains phytochemicals that inh...

This research investigated the effects of exogenous sodium nitroprusside (SNP) supplementation as nitric oxide (NO) on alleviating Pb-induced oxidative damage in lemon balm (Melissa officinalis L.) plants. Pb (100, 300 and 500 μM) alone and in combination with SNP (100 and 200 μM) were given to hydroponically grown Melissa officinalis L. plants. The findings suggested that in Pbtreated plants, ...

OBJECTIVE The aim of the present study was to investigate the neuroprotective effects of Melissa officinalis, a major antioxidant plant, against neuron toxicity in hippocampal primary culture induced by 3,4-methylenedioxymethamphetamine (MDMA) or ecstasy, one of the most abused drugs, which causes neurotoxicity. MATERIALS AND METHODS 3-(4,5-dimethyl-2 thiazoyl)-2,5-diphenyl-tetrazolium bromid...

The objective of this study was to determine the effect of a Melissa officinalis and Passiflora caerulea infusion on the severity of physiological chronic stress induced by movement restriction in CF-1 mice. 40 CF-1 male mice, six weeks of age, were divided into 4 groups (n = 10 for each group): (1) Group RS/MP received two treatments, induced stress through movement restriction and a infusion ...

Alzheimer's disease (AD) is a neurodegenerative disease that was characterized with deposit of beta amyloid (Aβ) aggregate in senile plaque. Oxidative damage to neurons and loss of cholinergic neurons in forebrain region are observed in this disease. Melissa officinalis is a medicinal plant from Lamiaceae family, used traditionally in the treatment of cognitive disorders. It has cholinomimetic ...

Article history: Received: 17Feb 2014. Accepted: 12Mar 2014 Available online: ........ ZJRMS 2015 Sep; ....(..): ...-.... Melissa officinalis (lemon balm) which belongs to the Lamiaceae family is a known herb that has long been used in traditional medicine to treat many disorders, and several studies have been conducted to identify the plant and its healing properties. The purpose of this artic...