Fernandes, J., and Pikaar, N. A. (1972). Archives of Disease in Childhood, 47, 41. Ketosis in hepatic glycogenosis. The occurrence of ketosis in 41 patients with liver glycogenosis and a control group of 22 children was investigated. Fasting ketosis was present in children with a deficiency of the debranching enzyme system and in young children with a deficiency of the phosphorylase system, but...

ever good the treatment, cases of true coma often die. Moreover, diabetic coma is rarely of acute onset ; at least twenty-four hours (and usually several days), elapse during which gross ketosis develops before the onset of loss of consciousness and circulatory collapse. The best insurance policy therefore in the prevention of diabetic coma is the regular testing of the urine for ketone bodies....

There is a theory of long standing that post-parturient dyspepsia of cattle, or bovine ketosis as it is often called, is caused by an inadequate calorie intake; the same has also been suggested of the condition known as pregnancy toxaemia in ewes. It was felt, therefore, that it might be of value to make a detailed study of starvation ketosis in those animals, especially as earlier experiments ...

A study involving a small number of cows found that the concentrations of insulin-like growth hormone 1 (IGF1) may be a useful predictor of metabolic disease. Further, IGF1 may provide also a pathophysiological link to metabolic diseases such as ketosis. The objective of the current study was to test whether the low antepartal total IGF1 or IGF1 binding protein (IGFBP) concentrations might pred...

The aim of this study in Tunisia was to classify ketosis-onset diabetes in adult patients. All patients aged > 30 years without known diabetes, presenting with ketosis and admitted to our department were studied. Patients with secondary or gestational diabetes and those on corticoid therapy or with coinciding infection were excluded. The data included clinical characteristics, immunological mar...

OBJECTIVE Most patients with ketosis-prone type 2 diabetes (KPD) discontinue insulin therapy and remain in near-normoglycemic remission. The aim of this study was to determine the effect of glucotoxicity on beta-cell function during remission in obese patients with KPD. RESEARCH DESIGN AND METHODS Age- and BMI-matched obese African Americans with a history of KPD (n = 8), severe hyperglycemia...

OBJECTIVE Over half of newly diagnosed obese African Americans with diabetic ketoacidosis (DKA) discontinue insulin therapy and go through a period of near-normoglycemia remission. This subtype of diabetes is known as ketosis-prone type 2 diabetes (KPDM). RESEARCH DESIGN AND METHODS To investigate the role of lipotoxicity on beta-cell function, eight obese African Americans with KPDM, eight obe...

Successful calving, healthy metabolic functions postpartum and good milk performance in lactation depend highly on the transition period (three weeks before and after calving) of dairy cows where they should be able to manage energy intake and overcome negative energy balance. Subclinical ketosis is one of the metabolic diseases associated with negative energy balance during the transition peri...

When rats are fasted they develop a ketonemia (ketosis) and frequently it is high enough to produce a measurable ketonuria. The height of the ket.osis is determined by many factors. When the diet is low in choline and in protein, the liver becomes very fatty (1) and the ketonuria on subsequent fasting is much higher (2,3) than it is in animals that have been on the stock diet or other food mixt...