BACKGROUND: The incidence and risk factors for diabetic ketoacidosis (diabetic ketoacidosis) and hyperglycemic hyperosmolar syndrome (hyperglycemic hyperosmolar syndrome, previously called non-ketotic hyperosmolar coma) have not been reported in a national population of renal transplant (renal transplantation) recipients. METHODS: We performed a historical cohort study of 39,628 renal transplan...

OBJECTIVE To evaluate whether adverse event reports to the US Food and Drug Administration on incidents of ketoacidosis from use of sodium glucose cotransport inhibitors (SGLT2 inhibitors) provide insight into ways this new class of drugs is being prescribed with other antihyperglycemic agents; to examine possible mechanisms to explain ketoacidosis. DESIGN AND METHODS Reports of adverse event...

Diabetes in acromegaly is usually non-insulin dependent and is secondary to insulin resistance caused by growth hormone excess. Diabetic ketoacidosis is a result of relative insulin deficiency and is a rare feature of acromegaly. We describe a case of acromegaly presenting with diabetic ketoacidosis. We demonstrate that growth hormone excess can cause diabetic ketoacidosis in the presence of re...

Chorea, hemichorea, hemiballismus and other parkinsonian movement disorders have been described in type 1 diabetic patient with uncontrolled hyperglycemia. In comparison, abnormal movements in diabetic ketoacidosis are rare though ketosis due to other causes can cause parkinsonism-like movement disorders. We report two cases of diabetic ketoacidosis where hemifacial spasm was the predominant cl...

in order to recognize of dka and its complications among children with dm type i, we conducted a descriptive study and all of the children with the final diagnosis of dka. data regarding their demographics, disease characteristics, treatment features and outcome derived from patients' medical files and registered in a data sheet. data were analyzed using spss 11.0 and exhibited in the form of f...

Acute esophageal necrosis is a rare cause of upper gastrointestinal bleeding, usually caused by hypoperfusion. In this report, we present a 34-year-old male patient suffering from acute esophageal necrosis presenting as hematemesis in a patient with Diabetic ketoacidosis. Diabetic ketoacidosis is rarely reported as a cause of acute esophageal necrosis and it is vital to diagnose it in a patient...

INTRODUCTION Ecstasy (3,4-methylenedioxymethamphetamin), a hallucinogenic amphetamine, is often used by young people, especially at 'raves'. This illicit drug can cause many metabolic changes and its use, when associated with prolonged exercise, may exacerbate ketoacidosis in type 1 diabetic patients. CASE PRESENTATION This is a case of ketoacidosis complicated by the use of ecstasy in a 19-y...

Diabetic ketoacidosis is characterized by hyperglycemia, anion-gap acidosis, and increased plasma ketones. After the resolution of hyperglycemia, persistent diuresis is rare. We herein report the case of a 27-year-old Asian woman with type 2 diabetes who was treated with a sodium-glucose cotransporter 2 (SGLT2) inhibitor (canagliflozin) who developed euglycemic diabetic ketoacidosis and persist...

Data from 191 post-mortem cases where post-mortem blood beta-hydroxybutyrate (βHB) and acetone concentrations and vitreous humor glucose concentrations (where available) had been measured were retrospectively investigated to determine the markers required to identify and distinguish between Alcoholic Ketoacidosis (AKA), Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycemic State (HHS). Blo...