Data Resource Profile: the Dutch National Intensive Care Evaluation (NICE) Registry of Admissions to Adult Intensive Care Units Nick van de Klundert, Rebecca Holman,* Dave A. Dongelmans and Nicolette F. de Keizer National Intensive Care Evaluation (NICE) Foundation, Amsterdam, The Netherlands, Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands, Department of ...

Appropriability mechanisms, innovation and productivity: Evidence from the UK Bronwyn H. Hall and Vania Sena Maastricht Economic and social Research institute on Innovation and Technology (UNU‐MERIT) email: [email protected] | website: http://www.merit.unu.edu Maastricht Graduate School of Governance (MGSoG) email: info‐[email protected] | website: http://mgsog...

Most of the adenosine triphosphate (ATP) synthesized during glucose metabolism is produced in the mitochondria through oxidative phosphorylation. This is a complex reaction powered by the proton gradient across the mitochondrial inner membrane, which is generated by mitochondrial respiration. A detailed model of this reaction, which includes dynamic equations for the key mitochondrial variables...

Mitochondria have long been known to sequester cytosolic Ca and even to shape intracellular patterns of endoplasmic reticulum -based Ca signaling. Accumulating evidence suggests that the mitochondrial network is an excitable medium which can demonstrate Ca induced Ca release via the mitochondrial permeability transition. The role of this excitability remains unclear, but mitochondrial Ca handli...