Spondylocostal dysplasia (Jarcho-Levin syndrome) comprises multiple malformations of the vertebrae and ribs coupled with a characteristic clinical picture of short neck, scoliosis, short trunk, and deformity of the rib cage. We describe a patient with the syndrome who also had spina bifida and diastematomyelia. We surmise that this association is not coincidental. Additional evidence is needed ...

2. JARCHO, SAUL, Human Palaeopathology, Proceedings of a Symposium on Human Palaeopathology held in Washington D.C., 14 January 1965. 3. M0LLER-CHRISTENSEN, V., 'A rosary bead used as tooth filling material in a human mandibular canine tooth. A unique case from the Danish middle ages', Proc. XXI Congr. internaz. Stor. Med., Siena, 22-28 September 1968, Rome, 1969. 4. WEmSS, D. L., and M0LLER-CH...

n engl j med 369;8 nejm.org august 22, 2013 754 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presente...

In 1938, Jarcho and Levin1 first described a syndrome of congenital abnormalities affecting the spine and the thorax. The syndrome described a spectrum of radiological and skeletal anomalies including abnormal vertebral segmentation or formation defects, rib deformities and short trunk dwarfism. In 1978, Solomon et al2 subdivided patients with the above features into 2 distinct phenotypes: spon...