BACKGROUND Only 25% of IVF transfer cycles lead to a clinical pregnancy, calling for continued technical progress but also more in depth analysis of patients' individual characteristics. The interleukin-1 (IL-1) system and matrix metalloproteinases (MMPs) are strongly implicated in embryo implantation. The genes coding for IL-1Ra (gene symbol IL-1RN), IL-1beta, MMP2 and MMP9 bear functional pol...

Previous reports have shown that the presence of hydrosalpinges may have a detrimental effect on in-vitro fertilization (IVF) outcomes and salpingectomy has been recommended by some authors as a means of improving IVF pregnancy rates. Our first objective was to determine the effect of hydrosalpinges diagnosed by ultrasound on IVF outcomes in our clinic. Our second objective was to examine the e...

OBJECTIVE The decision to use in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), or split insemination (IVF-ICSI) in the first cycle is based on the number of motile sperm. Hence, total fertilization failure (TFF) often occurs during IVF cycles, despite normozoospermia. To investigate whether the cumulative motile swim-up spermatozoa percentage at 22 hours post-insemination ...

OBJECTIVE To examine the utilization and outcomes of natural cycle (unstimulated) IVF as reported to the Society of Assisted Reproductive Technology (SART) in 2006 and 2007. DESIGN Retrospective analysis. SETTING Dataset analysis from the SART Clinical Outcome Reporting System national database. PATIENT(S) All patients undergoing IVF as reported to SART in 2006 and 2007. INTERVENTION(S)...

OBJECTIVE To determine the relationship between sperm chromatin structure assay (SCSA) parameters (DNA fragmentation index [DFI] and high DNA stainability [HDS]), and conventional IVF and IVF/intracytoplasmic sperm injection (ICSI) outcomes. DESIGN Retrospective review and prospective study. SETTING Private IVF clinic. PATIENT(S) Two hundred forty-nine couples undergoing first IVF and/or ...

OBJECTIVE To determine a successful method of selecting patients for natural cycle IVF combined with in vitro maturation (IVM) of immature oocytes and to determine treatment efficacy. DESIGN Retrospective analysis of IVF treatments. SETTING Hospital IVF clinic. PATIENT(S) Women with infertility according to ovarian reserve and endocrine profile were selected for different treatments. IN...

Objective: This research was aimed to explore the role of interventional embolization in hydrosalpin resulting from In Vitro Fertilization and Embryo Transfer (IVF-ET). Methods: From 2013 to 2016, 130 patients were treated with IVF-ET in which 75 were treated with fallopian tube embolization followed by IVF-ET while others received IVF-ET without other treatments. Age, basal Estradiol (E2) valu...

Infertility represents a national health problem in some African countries. Limited financial health resources in developing countries are a major obstacle facing infertility management. IVF is the definitive line of treatment for many couples. Stimulation cycles are associated with risks of ovarian hyperstimulation syndrome and multiple pregnancy. This study evaluates the client acceptability ...

BACKGROUND The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome. OBJECTIVE To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICSI cycle in patients who had recurrent IVF failure. MATERIALS AND MET...

The aim of this study was to investigate whether the sperm chromatin structure assay (SCSA) results after swim-up are related to fertilization rates, embryo quality and pregnancy rates following in vitro fertilization (IVF). A total of 223 couples undergoing IVF in our hospital from October 2008 to September 2009 were included in this study. Data on the IVF process and sperm chromatin structure...