The incidence of serious fungal infections has increased dramatically in recent decades. This increase is mainly due to the advent of HIV and to the increased use of cancer chemotherapy and of immunosuppressive therapies in organ transplantation [1,2]. The treatment of fungal diseases involves several classes of antifungal agents, among which the imidazoleor triazole-based drugs (referred to co...

Ye describe a direct, solid-phase AlA for 17a-hydroxyprolesterone (17-OH-P) that we are using to screen neonates Drcongenital adrenal hyperplasla. Phosphate buffer containrg danazol and anti-i 7-OH-P is placed in tubes coated with intibodyto IgG.Thetubesalsocontainstandards, controls, r bloodsamplesonfilterpaperdIscs 3 mm in dIameter. 1251. theled 17-OH-P is added to each tube. The mixture Is o...

A presente pesquisa buscou compreender as vivências dos servidores Técnico-Administrativos em Educação (TAEs) de uma Instituição Federal Ensino Superior (IFES), um contexto desflexibilização da jornada trabalho, à luz teoria Psicodinâmica do Trabalho. O processo é compreendido aqui como retorno trabalho que vez fora flexibilizada. Metodologicamente, recorreu-se ao uso triangulação metodológica ...

Dentre as categorias profissionais mais suscetíveis ao adoecimento está a dos da segurança pública. Nesse sentido, esse artigo tem por objetivo compreender condições, processos de trabalho e risco entre mulheres Polícia Militar do Rio Grande Norte (PMRN), Brasil. A pesquisa foi realizada com 20 policiais batalhão feminino cidade Natal-RN, que responderam um roteiro entrevista semiestruturado In...

The conception of a product is closely tied to its adaptation level to the users. In this view, designers are increasingly oriented to survey the needs and features of the users. This paper aims at developing a diagnosis of employees working in high-complexity activities in a petrochemical company, in light of the physical and operating changes in the Integrated Center of Control; assessing the...

Deep neural networks (DNNs) for supervised learning can be viewed as a pipeline of the feature extractor (i.e., last hidden layer) and linear classifier output that are trained jointly with stochastic gradient descent (SGD) on loss function (e.g., cross-entropy). In each epoch, true is estimated using mini-batch sampled from training set model parameters then updated gradients. Although latter ...

RESUMO Objetivo Analisar os indicadores de prazer e sofrimento no trabalho associados a depressão ansiedade entre agentes comunitários saúde (ACSs). Métodos Estudo transversal, qual variáveis dependentes foram presença sintomas depressão, avaliadas com o Patient Health Questionnaire (PHQ-9) Inventário Ansiedade Traço-Estado (IDATE). As independentes um questionário sociodemográfico Escala Indic...

Cohesion has been a topic of interest since structured design [20, 23] in the 1970’s. Today, there are numerous researchers continuing this work into object-oriented designs [1, 3, 5, 7, 9, 10, 12, 13, 16, 18, 19, 22]. Most of the current research has focused on the interaction of methods within a class, the inter-method cohesion. In this paper we consider both the inter-method cohesion and the...