^ By Suuoeon John O'Neill, M. D., M. Ch., Civil Surgeon, Shahpur. Forty miles distant from the shallt>ur Sadr is the village of Nowshera, approached by a road which in its last twenty miles runs a rough and uneven course over the hilis. Last winter, while inspecting the dispensary there, a man suffering from stone entreated me to afford him relief. He was in a pitiable condition, and could only...

Serious adverse drug reactions (SADRs) are caused by unexpected drug-human protein interactions, and some polymorphisms within binding pockets make the population carrying these polymorphisms susceptible to SADR. Predicting which populations are likely to be susceptible to SADR will not only strengthen drug safety, but will also assist enterprises to adjust R&D and marketing strategies. Making ...

Calcific aortic stenosis (AS) was initially characterized as a degenerative process (disorder) because of a tendency to describe any disorder that was not well understood and often occurred in the ‘elderly’ as degenerative. In the last ‘15–20’ years, the observation of the presence of risk factors for arterial atherosclerosis in patients with calcific AS, the production of aortic valve calcific...