Plastic materials play a pivotal role in modern society. Finding sustainable alternatives to established fossil-based polymers is an important part of the effort reduce environmental impact sector. 1,4:3,6-dianhydrohexitols (isosorbide, isomannide and isoidide) are group biobased diol monomers that promising for synthesis polyesters. Their rigid molecular structure imparts favorable material pr...

Seven patients with severe chronic congestive cardiac failure secondary to ischaemic heart disease performed submaximal supine exercise before and after 5 mg sublingual isosorbide dinitrate at the time of cardiac catheterisation. Exercise before isosorbide dinitrate produced a poor response in left ventricular performance. After isosorbide dinitrate this response was significantly improved. Com...

Isosorbide is a multi-purpose chemical that can be produced from renewable resources. Specifically, it has been investigated as replacement for toxic bisphenol A (BPA) in the production of polycarbonate (PC). In this study, synthesis isosorbide by sorbitol dehydration using cerium-based catalyst derived calcined cerium (IV) sulfate (300°C, 400°C, 450°C, 500°C, and 650°C) was investigated. The r...

The effects on portal pressure of the vasodilatory drugs isosorbide dinitrate and verapamil and of an alpha and beta blocking agent, labetalol, were assessed in 21 patients with cirrhosis and portal hypertension. The wedged hepatic venous pressure gradient (wedged minus free hepatic venous pressures) was used as an index of portal pressure and was not significantly changed by treatment with lab...

Central and regional hemodynamic studies were performed before and after the oral administration of 75 mg of hydralazine and/or 20 mg of isosorbide dinitrate in 15 patients with low-output congestive heart failure. Hydralazine increased mean cardiac output 17-25%, mean renal blood flow 19%, and limb blood flow 17% (all p < 0.05). Mean hepatic blood flow did not change significantly with hydrala...

Isosorbide is a biobased compound which could become in the near future an advantageous competitor of petroleum-derived components synthesis polymers different nature. When reactivity isosorbide not enough, it can be successfully transformed into secondary building blocks, such as bis(methyl carbonate), provides extra functionalities for polymerization reactions with diols or diamines. The pres...

As petroleum feedstocks start to dwindle, it is becoming more important to find acceptable replacements for materials made from these feedstocks. Polyurethanes have classically been synthesized from petroleum-based feedstocks, and depending on its properties, polyurethanes can be used in everything from foams, to construction plastics. In recent years there has been an increasing amount of rese...

Head-up tilt-table test is valuable in diagnosing type of syncope. Sensitivity varies in reports and is mostly poor. Isoproterenol or nitroglycerin is regularly used to increase head-up tilt-table test sensitivity. The aim of this study was to assess the value of sublingual isosorbide dinitrate administration before isoproterenol tilt test as a simple, practical test for diagnosis of neurally m...

The haemodynamic effects of dopamine and isosorbide dinitrate alone and in combination were studied in 8 patients with chronic congestive cardiac failure. In 7 patients dopamine, 6,tg/kg per min, increased mean cardiac index from 2-0 to 3 0 1/min per m2 (P < 0.0005); mean stroke volume index from 20 to 27 ml/m2 (P < 0.0025), and mean left ventricular stroke work index from 14 to 20 g M/M2 (P < ...

Different regioisomeric and diastereomeric isosorbide mono-epoxides are prepared polymerized to thermally stable relatively rigid biobased linear polyethers.