Pickering inverse emulsions of hydroxyl oligoethylene glycol methacrylate were stabilized in isopropyl myristate, a biofriendly oil, using surface-modified cellulose nanocrystals (CNCs) as stabilizing particles. The further polymerized by free or controlled radical polymerization (ATRP), taking advantage the bromoisobutyrate functions grafted on CNC surface. Suspension emulsion led to full bead...

Biocompatible oil-in-water (o/w) micro-emulsions can be prospective drug delivery vehicles for their capability to solubilize lipophilic (oil soluble) drugs in the dispersed oil. Plant oils are considered suitable for such a purpose. In this study, we have attempted to examine the dispersion of corn, cottonseed, clove, orange and peppermint oils, as well as isopropyl myristate (IPM) in water co...

Abstract This study aimed to determine all the extractives from Pinus nigra . Different samples were collected heartwood, sapwood and bark. A Soxlet device three different solvents (water, ethanol, dichloromethane) used collect extracts. Chemical analyses conducted with GC-MS (Agilent 5975C). The results revealed significant amounts of chemical compounds, such as phthalic acid, squalene, linole...

In developing of ointment for topical treatment of colds the structural and mechanical properties of the ointment bases contained isopropyl palmitate, beeswax and solid fat in different concentrations have been studied. Amount of isopropyl palmitate 60% remained constant and the ratio of solid fat and bee wax was varied. In order to study thixotropic properties the curve of kinetics deformation...

Abstract: Aim: The present work intends to formulate and evaluate film forming solution of diphenhydramine. Materials Methods: Film solutions (FFS) for transdermal delivery Diphenhydramine HCl were prepared using different polymers (hydroxypropyl cellulose, Eudragit L 100, polyvinylpyrollidone K30 K90), PEG 400 as plasticizer ethyl alcohol solvent. Results: found display an acceptable drying ti...

Background Psoriasis is a common chronic inflammatory skin disease characterized by erythematous and scaling plaques. The ongoing understanding of its pathogenesis has led to new therapeutic options and new areas of research which aimed at reducing keratinocyte proliferation and suppressing T-cell activation. Objectives To evaluate the efficacy and safety of topical use of a combined formulatio...

Background Psoriasis is a common chronic inflammatory skin disease characterized by erythematous and scaling plaques. The ongoing understanding of its pathogenesis has led to new therapeutic options and new areas of research which aimed at reducing keratinocyte proliferation and suppressing T-cell activation. Objectives To evaluate the efficacy and safety of topical use of a combined formulatio...

Gene therapy is in its development stage as a novel method for cancer treatment. Liposomes look promising as gene delivery vectors; however, investigations have shown that these vesicles are not doing well in some cases. It was decided here to investigate the possibility of augmentation of liposomal gene delivery by chemical penetration enhancers.Cationic liposome containing antisense oligonucl...

The development of low viscosity insulating liquids derived from natural esters is conducted in our laboratory. Nine monoesters, i.e., methyl myristate, ethyl isopropyl palmitate, stearate, and stearate were synthesized alcohols saturated fatty acids. Treatments performed to reduce water acid contents improve the oxidation stability monoesters. Some fundamental properties, such as breakdown vol...

The effect of polyethylene glycol 400 (PEG) dissolved at various concentrations (0-40% v/v) in water, on the interfacial transport of methyl nicotinate across an aqueous-isopropyl myristate interface was investigated with a rotating diffusion cell. At four temperatures studied (20-37 °C), the presence of PEG decreased the rate of solute transfer both into and out of the organic phase in a conce...