Various approaches to solvent recovery have been studied for the manufacturing process of celecoxib, the active ingredient in Celebrex. A design case study has been performed by Rowan University with Pfizer through a green engineering partnership program. The manufacturing operation at Barceloneta, Puerto Rico was evaluated and several green engineering alternatives for the purification and rec...

The vanadate anion in the presence of pyrazine-2-carboxylic acid (PCA) was found to effectively catalyze the oxidation of isopropanol to acetone with hydrogen peroxide. The electronic spectra of solutions and the kinetics of oxidation were studied. The conclusion was drawn that the rate-determining stage of the reaction was the decomposition of the vanadium(V) diperoxo complex with PCA, and the...

Isopropanol is the second most common cause of short-chain alcohol acute intoxication. Nonethanolic short-chain alcohols mediate their immunomodulatory effect by interfering with nuclear factor of activated T cells (NFAT) activation with or without additional activator protein-1 (AP-1) involvement. In the present study, we examined the immunomodulation induced by isopropanol in conditions that ...

Background The formation of by-products, mainly acetone in acetone-butanol-ethanol (ABE) fermentation, significantly affects the solvent yield and downstream separation process. In this study, we genetically engineered Clostridium acetobutylicum XY16 isolated by our lab to eliminate acetone production and altered ABE to isopropanol-butanol-ethanol (IBE). Meanwhile, process optimization under pH...

The present study demonstrates a green process for the synthesis of spherical-shaped and stabilized silver nanoparticles Ag NPs using gamma irradiated conditions. This method has certain advantages over conventional methods since it can manage particle size structure generates totally reduced extremely pure free from by-products or chemical reducing agents. Silver composite (Ag / CM) is prepare...

Ionic and covalent cross-linking of an acid–base blend is used to manufacture membranes with high stability against dissolution reduced isopropanol acetone crossover for direct-isopropanol fuel cell applications.

Ni/CeO2 catalysts were synthesized by the coprecipitation method in a basic medium, using different solvents: water, methanol, ethanol, and isopropanol (Ni content, 10% wt.). These tested production of syngas through oxidative reforming methane (ORM), partial oxidation (POM). The results this research demonstrated that use alcohols (methanol, isopropanol) during preparation method, improved the...

O mercado de própolis brasileiro sofreu grande expansão, levando o setor beneficiamento a buscar melhor forma produzir extratos com atividades biológicas. objetivo deste trabalho foi otimizar extração verde pela atividade antifúngica e realizar incorporação em um biofilme quitosana. Os foram preparados utilizando etanol, acetona, acetato etila isopropanol, acordo três planejamentos, concentraçã...