LnDOTA-tetraamide complexes typically exist in solution as a mixture of square-antiprismatic (SAP) and twisted square-antiprismatic (TSAP) coordination isomers. In most cases, the SAP isomer, which is preferred for CEST imaging, predominates, and the presence of the minor TSAP isomer is assumed to have little influence on quantitative measures of the water-exchange rate constant for the SAP iso...

the volatile constituents of aerial parts of euphorbia aellenii rech.f. and e. microsciadea boiss. were analyzed by gas chromatography (gc) and gc-mass spectrometry (ms) methods. the main volatile constituents of e. aellenii were phytol isomer (47.3%), camphene (31.9%) and caryophyllene oxide (20.6%), while the major volatile components of e. microsciadea were trans-anethole (74.5%), limonene (...

catalytic osmylation of cis and trans 2-cyclohexene-cyclohexanol (1a) and (1b) are carried out in the presence of n-methyl morpholine-n-oxide. under the same conditions, only the cis isomer reacted, leading to triol (3). the steric hindrance of the equatorial oh group probably prevents the trans isomer from entering into such reaction. triol (3) was also obtained from the reduction of the diol-...

microstructural investigation of low molecular weight 1,4-polybutadiene (1,4-pbd) was studied by 1h and 13c nuclear magnetic resonance spectroscopy (nmr). the isomer contents of 1,4-cis, 1,4-trans and 1,2- vinyl in polybutadiene microstructure were determined. the number average molecular weight for low molecular weight polybutadiene was measured by nmr techniques and comparison was made with g...

We describe the applications of localization methods, in particular the functorial localization formula, in the proofs of several conjectures from string theory. Functorial localization formula pushes the computations on complicated moduli spaces to simple moduli spaces. It is a key technique in the proof of the general mirror formula, the proof of the Hori-Vafa formula for explicit expressions...

1. The urinary excretion of isomers I and I11 of coproporphyrin by fifty-nine patients with Dubin-Johnson syndrome has been examined, and compared with the results obtained for normal control subjects and patients with various types ofjaundice. 2. The control subjects (with one exception) excreted less than 45% of the coproporphyrin as isomer I. Fifty-six patients with the Dubin-Johnson syndrom...

This paper introduces the concept of an isomer network based on the reaction step counts between pairs of isomers as an alternative means to view and analyze isomer space. The computation of isomer networks is computationally expensive with respect to both run time and memory. Accordingly, this paper focuses on the design of algorithms to compute isomer networks and their analysis on structural...

The metabolism of Y-nilroso-A'-nictliyl\-(2-ovcipn>pyl)aminc was ex amined using freshly isolated hepatocytes from Fischer 344 rats. As determined by high performance liquid chromatography, it was found that the E isomer was preferentially metabolized when the parent mixture was used. When the two isomers were studied separately, the E isomer was efficiently metabolized in the hepatocytic syste...

Urinary coproporphyrinisomer distribution was studied in 13 patients suffering from the Dubin-Johnsonsyndromeand several control groups. In patients with the DubinJohnson syndrome the isomer distribution was quite the reverse to that of normal persons. The urinary isomer distribution was in the normal range in patients with Gilbert’s syndrome, hemolytic jaundice, and fatty liver. In many patien...

Dobutamine and its stereoisomers were evaluated for alpha and beta adrenergic activities in vitro. The racemate and the (--)-isomer were found to be potent partial agonists of alpha adrenergic receptors in rat aorta. The (+)-isomer lacked alpha agonist activity. The affinities of (+/-)-, (+)- and (--)-dobutamine for the alpha adrenergic receptor were high (--log KB values of 7.01, 7.02 and 7.07...