Mitochondria play an important role in energy production for the cell. The proper function of a myocardial cell largely depends on the functional capacity of the mitochondria.  Therefore it is necessary to establish a novel and reliable method for a non-invasive assessment of mitochondrial function and metabolism in humans. Although originally designed for evaluating myocardial perfusion, 99mTc...

Desmin-related myopathy (DRM) is known to cause different types of cardiomyopathy. Late gadolinium enhancement cardiovascular magnetic resonance (CMR) has been shown to identify fibrosis in ischemic and non-ischemic cardiomyopathies. We present a rare case of desmin-related hypertrophic cardiomyopathy, CMR revealed fibrosis in the lateral wall of the left ventricle. CMR is superior to conventio...

discussion there are other causes of dilated cardiomyopathies which could be transient like peripartum cardiomyopathy. the development of biventricular mural thrombi is rare, and it mainly increases the risk of embolization in the systemic and pulmonary circulations. case presentation we present two case reports of post-myocardial infarction sequel leading to ischemic cardiomyopathy and peripar...

We present a case of successful percutaneous epicardial access in patients with non-ischemic cardiomyopathy limited mapping and ablation the ventricular tachycardia substrate on surface.

Pheochromocytoma (PC) is a tumor of chromaffin cells the sympathetic-adrenal system that produces large amount catecholamines (adrenaline, norepinephrine, dopamine). There are no reliable data in literature on frequency cardiac manifestations pheochromocytoma, which associated with rarity this pathology. This case demonstrates development catecholamine-induced cardiomyopathy, proceeding under g...

Stem cell therapy for heart failure is a rapidly progressing field. The objective of this study was to assess the safety, and short-term results of thoracoscopic direct injection of angiogenic cell precursors into patients with endstage cardiomyopathy. Cells were obtained from the patient's own blood, avoiding immunological concerns. The number of cells prior to injection was 29.1 +/- 18.9 x10(...

Background Left ventricular ejection fraction (LVEF) is a strong predictor of subsequent cardiovascular events in patients with ischemic and non-ischemic cardiomyopathy. CMR is an excellent technique for assessment of LVEF as well as for the detection of myocardial scar. We sought to evaluate if the presence of myocardial scarring in nonischemic cardiomyopathy could be an important predictor of...

Purpose The aim of this study was to determine the predict factors of the therapeutic response in left ventricular ejection fraction (LVEF) and remodeling in patients with non-ischemic cardiomyopathy who were receiving treatment with b blockers. We hypothesized LGE by CMR imaging predicted therapeutic response in LVEF and remodeling in patients with non-ischemic cardiomyopathy who were receivin...

  Transient ischemic left ventricular dilation (TID) is a marker of severe and extensive coronary artery disease as well as an increased risk of adverse outcomes. The patients with more severe and extensive ischemia, multivessel-type of perfusion abnormality as well as patients with left anterior descending artery (LAD) territory perfusion abnormality have more probab...

Although ischemic cardiomyopathy is commonly caused by chronic obstructive coronary disease, the mechanism of the cause is still under investigation. We present echocardiographic strain, magnetic resonance, and histology findings in a chronic ischemia model in preclinical study. This case illustrates the features of multimodality imaging in chronic obstructive coronary disease and gives us grea...