نتایج جستجو برای: ischemiareperfusion injury

تعداد نتایج: 317346  

Journal: :Circulation 2012
Marc S Penn Megan Kamath

The pathophysiology of multiple disease states, including sepsis,1,2 hypertension,1 atherosclerosis,3–5 and ischemiareperfusion injury,6 is characterized by loss of the endothelial barrier function leading to the accumulation of plasma-borne proteins, tissue edema, and cell death. Importantly therapeutic strategies that inhibit loss of endothelial barrier function have been associated with stra...

2003
Laura Calabresi Giuseppe Rossoni Monica Gomaraschi Francesca Sisto Ferruccio Berti Guido Franceschini

The incidence and severity of primary cardiac events are inversely related to the plasma concentration of high-density lipoproteins (HDLs). We investigated whether HDLs may exert a direct cardioprotection in buffer-perfused isolated rat hearts, which underwent a 20-minute low-flow ischemia followed by a 30-minute reperfusion. The administration of HDLs at physiological concentrations (0.5 and 1...

1999
ANNA BÖRJESSON ANDREAS NORLIN XIANGDONG WANG ROLAND ANDERSSON HANS G. FOLKESSON Andreas Norlin Xiangdong Wang

Börjesson, Anna, Andreas Norlin, Xiangdong Wang, RolandAndersson, and Hans G. Folkesson. TNF-a stimulates alveolar liquid clearance during intestinal ischemiareperfusion in rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 278: L3–L12, 2000.—Intestinal ischemia-reperfusion commonly occurs in critically ill patients and may lead to the development of remote organ injury, frequently involving the lu...

1999
ANNA BÖRJESSON ANDREAS NORLIN XIANGDONG WANG ROLAND ANDERSSON HANS G. FOLKESSON Andreas Norlin Xiangdong Wang

Börjesson, Anna, Andreas Norlin, Xiangdong Wang, RolandAndersson, and Hans G. Folkesson. TNF-a stimulates alveolar liquid clearance during intestinal ischemiareperfusion in rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 278: L3–L12, 2000.—Intestinal ischemia-reperfusion commonly occurs in critically ill patients and may lead to the development of remote organ injury, frequently involving the lu...

2003
Guido Franceschini Laura Calabresi Giuseppe Rossoni Monica Gomaraschi Francesca Sisto Ferruccio Berti

The incidence and severity of primary cardiac events are inversely related to the plasma concentration of high-density lipoproteins (HDLs). We investigated whether HDLs may exert a direct cardioprotection in buffer-perfused isolated rat hearts, which underwent a 20-minute low-flow ischemia followed by a 30-minute reperfusion. The administration of HDLs at physiological concentrations (0.5 and 1...

2014
Cao Su Tao Xia Shen Ren She Qing Ding Jing Huang Lian Qin Bin Zhou Yuan Zhu Xiang

and it is an important factor that leading to cardiac ischemiareperfusion injury. In the past, most attention was focused on cardiac cells. While in recent years, myocardiac microvascular endothelial cells (MMECs) attracted scholar’s attention. The one hand, endothelial cells participate in many important body balance regulation, and can synthesize and secrete a variety of biologically active s...

2002
YOSHIHITO TAKAHASHI RAYMOND W. GANSTER ANDREA GAMBOTTO LIFANG SHAO TAKASHI KAIZU TONG WU GAUTAM P. YAGNIK ATSUNORI NAKAO GEORGE TSOULFAS TAKASHI ISHIKAWA TOYOKAZU OKUDA DAVID A. GELLER NORIKO MURASE Thomas E. Starzl Raymond W. Ganster Andrea Gambotto Lifang Shao Takashi Kaizu Tong Wu Atsunori Nakao George Tsoulfas Takashi Ishikawa Toyokazu Okuda David A. Geller

Takahashi, Yoshihito, Raymond W. Ganster, Andrea Gambotto, Lifang Shao, Takashi Kaizu, Tong Wu, Gautam P. Yagnik, Atsunori Nakao, George Tsoulfas, Takashi Ishikawa, Toyokazu Okuda, David A. Geller, and Noriko Murase. Role of NFB on liver cold ischemiareperfusion injury. Am J Physiol Gastrointest Liver Physiol 283: G1175–G1184, 2002. First published July 17, 2002; 10.1152/ajpgi.00515.2001.—The r...

2014
Liara M. Gonzalez Adam J. Moeser Anthony T. Blikslager

Gonzalez LM, Moeser AJ, Blikslager AT. Animal models of ischemiareperfusion-induced intestinal injury: progress and promise for translational research. Am J Physiol Gastrointest Liver Physiol 308: G63–G75, 2015. First published November 20, 2014; doi:10.1152/ajpgi.00112.2013.—Research in the field of ischemia-reperfusion injury continues to be plagued by the inability to translate research find...

Journal: :The American journal of physiology 1998
Klaus Kusterer Jörg Bojunga Michael Enghofer Edmund Heidenthal Klaus H Usadel Hubert Kolb Stephan Martin

Ischemia-reperfusion injury is a pathogenic factor in the course of many clinical disorders, such as myocardial infarction, stroke, organ transplantation, burns, and circulatory shock. The extent of ischemia-reperfusion injury is dependent on the number of infiltrating leukocytes. With in vivo microscopy, we evaluated the effect of the recombinant form of soluble murine intercellular adhesion m...

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