Mucosal uptake, mucosal transfer, and retention of a physiological dose of ferrous iron were studied in women with active rheumatoid arthritis (RA): 19 with normal and 17 with depleted bone marrow iron stores. Control subjects were 26 normal women and 20 women with uncomplicated iron deficiency. Iron absorption was measured with 59Fe as a tracer and by whole body counting. Compared with control...

BACKGROUND Alcohol increases body iron stores. Alcohol and iron may increase oxidative stress and the risk of alcohol-related liver disease. The relationship between low or "safe" levels of alcohol use and indices of body iron stores, and the factors that affect the alcohol-iron relationship, have not been fully characterized. Other aspects of the biological response to alcohol use have been re...

objectives: breath holding spells are one of the most frequent and important diagnostic challenges in pediatrics. the aim of this study, conducted on pediatric patients referring to the pediatric neurology clinic in hormozgan province, was to evaluate therapeutic effects of iron on breath holding spells materials and methods: 35 children (19 males and 16 females), aged between 3 to 60 months, w...

AIMS To identify how many particles should be examined to enable a confident assessment of the presence or absence of iron stores and the quantity of iron in a bone marrow aspirate to be made. METHODS One hundred and ninety consecutive bone marrow aspirate samples were stained with Perls' stain and the iron content of 10 consecutive particles was recorded. The first particle found to be posit...

Iron deficiency is one of the most common nutritional problems in the world, It is frequently found in both developed and developing countries and mainly affects women of childbearing age. The aim of this study was to investigate the relationship of iron deficiency anemia in pregnant women on neonatal weight. The study subjects were a group of 241 women aged between 20 and 34 years who wer...

Background: Coronary heart disease is a common disease after adolescence. Strong epidemiological evidence is available that iron is an important factor in coronary artery disease. Therefore this study was done to assess the relationship between iron stores and coronary artery disease. Materials and methods: 208 subjects with cardiovascular disease were included in the study. Personal informati...

Determination of serum ferritin is an important means of assessing body iron stores. Trace amounts of ferritin normally present in serum are detectable by sensitive radioimmunoassay techniques or an enzyme immunoassay procedure. Ferritin normally accounts for no more than a very small fraction of the total iron in serum, but generally maintains a stable concentration that is proportional to the...

Epidemiologic studies have found a relation between body iron stores and risk of chronic disease. Iron-absorption studies from single meals have shown that many dietary factors can influence nonheme-iron bioavailability. However, little is known about the association of these dietary factors with iron stores in free-living elderly populations. To address this question, we investigated the consu...

A Perls’ or Prussian blue stain (Figs 2.1 and 2.2) demonstrates haemosiderin in bone marrow macrophages and within erythroblasts. Consequently, it allows assessment of both the amount of iron in reticulo-endothelial stores and the availability of iron to developing erythroblasts. Assessment of storage iron requires that an adequate number of fragments are obtained. A bone marrow film or squash ...

CONTEXT Pregnant women are often iron deficient, and iron deficiency has adverse effects on thyroid metabolism. Impaired maternal thyroid function during pregnancy may cause neurodevelopmental delays in the offspring. OBJECTIVE Our objective was to investigate whether maternal iron status is a determinant of TSH and/or total T(4) (TT4) concentrations during pregnancy. DESIGN AND OUTCOME MEA...