The present study demonstrated genetic analysis of human leukocyte antigen (HLA) in a familial Graves' disease linked to autoimmune mechanism. The proband was a 17 year-old female. At 15 years, Graves' disease was diagnosed with serum TSH was <0.015 IU/ml; free T(3), 13.6 pg/ml; free T(4), 4.51 ng/dl; and TSH receptor antibody (TRAb), 94.1%. She had two brothers (19 and 13 years-old), who manif...

Type 1 diabetes mellitus (T1DM) results from autoimmune destruction of insulin-producing beta cells and is characterised by the presence of insulitis and &and beta-cell autoantibodies. Up to one third of patients develop an autoimmune polyglandular syndrome. Fifteen to 30% of T1DM subjects have autoimmune thyroid disease (Hashimoto's or Graves' disease), 5 to 10% are diagnosed with autoimmune g...

PURPOSE To assess quality of life and depressive status in Korean patients with Graves' ophthalmopathy. METHODS A cross-sectional study of 49 patients (mean age, 41 years; sex ratio, M:F=11:38) with Graves' ophthalmopathy (referred to as the Graves' group) and 48 age-matched and sex-matched controls (mean age, 40.2 years; sex ratio, M:F=11:37) was performed using the Korean version of the 36-...

Human and animal skeletal remains can provide information about the food chain of inhabitant’s nutrition of archaeologicalsites. The food chain which at it minerals and organic materials transferred from soil to the plants, from plants to theanimals, and from herbivores animals to the carnivores, is the benchmark system in ancient diet. Although Chemicalinteractions between soils, animal and hu...

OBJECTIVE Graves' disease and Hashimoto's thyroiditis are the most common causes of hyper and hypothyroidism, respectively. Differentiation of these 2 diseases, if the patient is euthyroid, may sometimes be extremely difficult on the basis of clinical and laboratory findings. The purpose of this study was to determine the sensitivity and specificity of gray scale sonography in differentiation o...

OBJECTIVE To determine the role of peak systolic velocity, end-diastolic velocity and resistance indices of both the right and left inferior thyroid arteries measured by color-flow Doppler ultrasonography for a differential diagnosis between gestational transient thyrotoxicosis and Graves' disease during pregnancy. METHODS The right and left inferior thyroid artery-peak systolic velocity, end...

At the end of 4th century BC, and beginning 3rd BC a Celtic population wave reached eastern parts Carpathian Basin, including Northeastern Hungary. The elements funerary rite archaeological finds attest to presence newly arrived communities in cemeteries region. present study serves as preliminary report on research results cemetery Hernád valley excavated 2019. site Novajidrány–Sárvár-erdészhá...

BACKGROUND/AIM Graves-Basedow disease is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing Graves-Basedow disease between the groups of individuals with and without Graves-Basedow disease, and to compare the presence of risk factors between the affe...

A 52-year-old woman was referred to our hospital for analysis of iron deficiency anaemia. Her medical history revealed extirpation of a meningeoma, Graves’ disease and atrial fibrillation. She had no complaints. Physical examination was normal. Laboratory investigations revealed microcytic anaemia (haemoglobin 7.3 mmol/l, mean cell volume 76 fl) and iron deficiency (ferritin 15 μg/l, normally >...