objective macular corneal dystrophy (mcd) is a rare autosomal recessive disorder affecting the stroma of cornea. most cases of mcd are caused by mutations in chst6 gene. the aim of this study was to determine mutations in the carbohydrate sulfotransferase 6 gene (chst6) through genetic analysis of 7 iranian patients with mcd. materials & methods we screened the chst6 gene to determine the range...

BACKGROUND Human cytomegalovirus (HCMV) infections are a major cause of morbidity and mortality among immunocompromised patients. Prolonged antiviral therapy is a cause of mutation and drug resistance in the HCMV genome. OBJECTIVES The aim of this study was to identify resistance to ganciclovir (GCV) in Iranian immunosuppressed patients at two different stages of the disease: early (before GC...

The physician's acquittal has obsessed Iranian legislator's mind to a large extent. This is exclusively observed in Iranian statuses and specifically in Shi'ite school of though. Muslim jurists' opinions play a very important role in enacting legal articles related to it. After reviewing the literature, the authors tried to pick and collect common features of physician's responsibilities and du...

BACKGROUND Investigating the prevalence of diseases and causes of hospitalization of Iranian pilgrims in Iraq can be helpful for healthcare programmers in scheduling a healthy and joyful trip for pilgrims and reducing their mortality and morbidity. OBJECTIVES The main purpose of this study was to determine the frequency of Iranian pilgrims' referral cases to Karbala and Najaf hospitals in Ira...

References 1. Zolfaghari M, Mousavifar SA, Haghani H: Mobile phone text messaging and Telephone follow-up in type 2 diabetic patients for 3 months: a comparative study. J Diabetes & Metabolic Disorders 2012, 11:7. 2. Zolfaghari M, Mousavifar SA, Pedram S: Mobile Phone Text Messaging and Telephone Follow-Up in Iranian Type 2 Diabetic Patients for 3 Months: A Comparative Study. Iranian J Diabetes...

318 Iranian Journal of Kidney Diseases | Volume 6 | Number 4 | July 2012 kidney calculi, the clinical features and risk factors of urolithiasis were evaluated.1 They concluded that urolithiasis remains a serious problem in Iranian children. In addition, family history of urolithiasis, urologic abnormalities, metabolic disorders, and urinary tract infections were associated risk factors for pedi...

BACKGROUND Non-Hodgkin lymphoma (NHL) includes a wide range of diseases with different clinical and biological features. NHL is usually presented as localized or generalized lymphadenopathy. It has been suggested that the HLA class I and II are associated with susceptibility to NHL. Different ethnic groups have been found to have different HLA class I and II alleles which affect NHL. OBJECTIV...

PURPOSE To investigate whether microRNA (MIR)-184 mutations make a substantial contribution to keratoconus (KCN) among affected Iranian patients. METHODS A total of 47 Iranian KCN patients, diagnosed based on family history, clinical examinations using slit lamp biomicroscopy, refraction and corneal topography were enrolled in this study. The pri-miR-184 encoding gene obtained from the DNAs o...

BACKGROUND Quality of life is of significant importance in chronic hepatitis B (CHBV). We aimed to assess the psychometric properties of the Hepatitis B Quality of Life Questionnaire v1.0 (HBQOL) in a large sample of 320 Iranian patients with CHBV. METHODS After adapting the Iranian version through forward-backward translation and expert panel discussion, we administered HBQOL together with S...

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), also named as autoimmune polyglandular syndrome (APS) type 1, is a rare autosomal recessive disorder caused by mutations in autoimmune regulator (AIRE) gene. It is distinguished by an immune-mediated damage of endocrine tissues, chronic candidiasis, and ectodermal disorder. APECED has been shown to be frequent in some popu...