OBJECTIVE The aim of this study was to investigate the characteristics of power Doppler (PD) subclinical synovitis in patients with RA who achieve clinical remission free from physical synovitis. METHODS Twenty-nine RA patients were consecutively enrolled. All of the patients had achieved clinical remission [simplified disease activity index (SDAI) 3.3] for at least 6 months at the musculoske...

OBJECTIVE To investigate whether, there is an association between consumption of fruit and vegetables and dietary antioxidants and the risk of developing inflammatory polyarthritis (IP). METHODS In a prospective, population based, nested case-control study of residents of Norfolk, UK, men and women aged 45-74 years were recruited, between 1993 and 1997 through general practice age-sex registe...

conclusions bilateral anterior shoulder dislocation is rare. it could be undiagnosed, especially when there is no clear history of major trauma. by awareness of such unusual possibility, early diagnosis, treatment, and reduction can provide desirable outcome. introduction shoulder dislocation is the most common presentation of joint dislocation in emergency department (ed). bilateral shoulder d...

The Norfolk Arthritis Register (NOAR) has been re c ruiting and fo l l ow i n g patients with early inflammatory poly-arthritis (IP) since 1989. Approximately thre e-q u a rt e rs of the patients fo l-lowed satisfy classification criteria for rheumatoid arthritis (RA) by 5 years from symptom onset. This paper sum-m a rises the publ i c ations wh i ch have been based on the NOAR cohort with resp...

OBJECTIVE Obesity has been associated with disease outcomes in inflammatory arthritis. This study aimed to investigate cross-sectionally the relationship between body mass index (BMI) and functional disability in a large inception cohort of patients with early inflammatory polyarthritis (IP). METHODS Patients age ≥16 years with ≥2 swollen joints for ≥4 weeks were recruited into the Norfolk Ar...

Purpose: This study aimed to explore underlying action mechanism of Wu-Tou decoction (WTD) in rheumatoid arthritis (RA) through network pharmacology prediction and experimental verification. Methods: Chemical compounds and human target proteins of WTD as well as RA-related human genes were obtained from TCM Database @ Taiwan, PubChem and GenBank, respectively. Subsequently, molecular networks a...

The major cause of disability is stroke. It is the second highest cause of death after coronary heart disease in Australia. In this paper, a post stroke therapeutic device has been designed and developed for hand motor function rehabilitation that a stroke survivor can use for bilateral movement practice. A prototype of the device was fabricated that can fully flex and extend metacarpophalangea...

This paper describes a new approach allowing the generation of a simplified Biped gait. This approach combines a classical dynamic modeling with an inverse kinematics’ solver based on particle swarm optimization, PSO. First, an inverted pendulum, IP, is used to obtain a simplified dynamic model of the robot and to compute the target position of a key point in biped locomotion, the Centre Of Mas...

Introduction: Inflammatory joint diseases are common in elderly, and regulation of joint blood flow (JBF) is important in these conditions. The aim of this study was to investigate the response of inflamed joint blood vessels to angiotensin (Ang ), a vasoconstrictor factor which has been shown to be produced in inflamed joints locally. Identification of Ang receptor subtypes in joint blood ve...