Two types of radiations are used for preservation. They are ionizing radiations such as cathode and gamma rays and nonionizing radiation such as infrared and UV rays. The latter two have poor penetration and bactericidal properties. Ionizing radiations act by disrupting progeny cycles of pathogenic microorganisms by destroying DNA/RNA cycles. Thus, it enhances shelf-life of food and reduces mic...

Densely ionizing radiations interact with DNA to cause heavily clustered sites of damage that are difficult to repair correctly. We have been able to determine for the first time the breakpoints of several very large deletions induced by densely ionizing radiation in diploid human cells and show that damage clustering is reflected in the complexity of mutations. Intra- and interchromosomal inse...

The detrimental consequences of radiation are referred to as radiation damage. To understand the effects of radiation, one must first be familiar with the radiations and their interaction mechanisms. Further, the fundamental characteristics of the material(s) being irradiated must also be understood. A brief summary of the characteristics of radiation is first presented below. This is followed ...

BACKGROUND Production of high levels of IL-6 is often correlated with resistance to cytotoxics or ionizing radiations, in cancer cell lines as in various cancer patients. We investigated whether monoclonal antibodies directed against IL-6 may enable to reverse resistance of cancer cell lines. METHODOLOGY/PRINCIPAL FINDINGS We exposed ten haematological cancer cells from lymphoma, myeloma, or ...