Iodine-131 is successfully used in the treatment of hyperthyroidism and differentiated thyroid cancer. Thyroid is the critical organ for iodine. Iodine is taken up by the thyroid follicular cells. Radioactive isotope iodine-131 simultaneously emits two types of radiation: radiation beta minus (β-) used for the treatment and gamma (γ) used for diagnosis. Due to the penetration of beta particles ...

An air- and moisture-stable fluoroiodane in the presence of AgBF4 is suitable for selective geminal difluorination of styrenes under mild reaction conditions. One of the CF bonds is formed by transfer of electrophilic fluorine from the hypervalent iodine reagent, while the other one arises from the tetrafluoroborate counterion of silver. Deuterium-isotope-labelling experiments and rearrangemen...

PURPOSE Several isotopes are available for low dose-rate brachytherapy of the prostate. Currently, most implants use a single isotope. However, the use of dual-isotope implants may yield an advantageous combination of characteristics such as half-life and relative biological effectiveness. However, the use of dual-isotope implants complicates treatment planning and quality assurance. Do the ben...

Currently, thirty-eight palladium, thirty-eight antimony, thirty-nine tellurium, thirty-eight iodine, and forty xenon isotopes have been observed and the discovery of these isotopes is discussed here. For each isotope a brief synopsis of the first refereed publication, including the production and identification method, is presented. ∗Corresponding author. Email address: [email protected]...

To measure the small amounts of iodine in tissues, organelles, and subfractions it is necessary to use very sensitive and specific analytical methods. Neutron activation analysis meets these criteria; the measurement of lZ81 after irradiation of the naturally occurring isotope, 1271, has a sensitivity of about 0.08 nanogram (12). However, neutron activation analysis has the disadvantage of requ...

An inductively coupled mass spectrometric method was developed for the direct determination of iodine in urine. The application of isotope dilution analysis with added 129I offers new possibilities for automatic and accurate determinations. The sample preparation consists of dilution with an ammonia solution containing 129I. The validation was made by comparison with the results obtained in ano...

Concentrations and species of iodine isotopes ((127)I and (129)I) provide vital information about iodine geochemistry, environmental conditions and water masses exchange in oceans. Despite extensive investigations of anthropogenic (129)I in the Arctic Ocean and the Nordic Seas, concentrations of the isotope in the Atlantic Ocean are, however, still unknown. We here present first data on (129)I ...

The physico-chemical form in which the secretion of the thyroid gland exists in blood is not well understood. It is generally believed to be associated in some manner with the plasma proteins since the iodine content of precipitated washed plasma protein (1) and the rate of turnover of 131 in this protein appears to vary with the state of thyroid activity (2). The observation of Trevorrow (3) t...

Nuclear medicine would be greatly aided if compounds were available to promote the excretion of unwanted radioisotopes from biological systems. Such preparations would make possible greater use of long-lived radionuclides in medicine and would reduce some of the environmental hazards associated with nuclear energy. The biochemistry of radioisotope excretion is complicated because there are so m...