The antibody-mediated targeted delivery of cytokines to sites of disease is a promising avenue for cancer therapy, but it is largely unexplored for the treatment of chronic inflammatory conditions. Using both radioactive and fluorescent techniques, the human monoclonal antibodies L19 and G11 (specific to two markers of angiogenesis that are virtually undetectable in normal adult tissues) were f...

global health 2035, the report of the lancet commission on investing in health, laid out a bold, highly ambitious framework for making rapid progress in improving global public health outcomes. it showed that with the right health investments, the international community could achieve a “grand convergence” in global health—a reduction in avertable infectious, maternal, and child deaths down to ...

" …let me say that I hope we keep our voice clear and strong on the central task of raising the health of the poor. I can be 'realistic' and 'cynical' with the best of them—giving all the reasons why things are too hard to change. We must dream a bit, not beyond the feasible but to the limits of the feasible, so that we inspire. I think that we are an important voice speaking on behalf of the w...

Human resources for health are necessary to the delivery of health services; only by securing a sufficient, equitably distributed, adequately supported and well-performing health workforce can any health goals and targets set by national governments or the international community be met [1]. In spite of the recognition of this central role in attaining health outcomes, investments in human reso...