Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is mostly targeted to a subset of transcription units (gene bodies). In a drastic contrast, vertebrate genomes are generally globally and heavily methylated, punctuated by the limited local hypo-methylation of putative regulatory...

This report shows for the first time, the evidence of IL6 gene in an Echinodermata, so in an Invertebrate. It recalls also the existence of IL2 gene, we have found also in the Ophuirid: Ophiocomina nigra, the sister of the Asterid: Asterias rubens. All these animals belong to Echinodermata.

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