purpose: to evaluate the influence of different confounding factors on the effect of intravitreal triamcinolone acetonide injection for refractory diabetic macular edema. methods: in a prospective placebo-controlled randomized clinical trial, 88 eyes with refractory diabetic macular edema were randomly assigned into two groups including 45 in the treatment group (4 mg intravitreal triamcinolone...

Correspondence: Pier Enrico Gallenga University Eye Clinic, G.D’Annunzio University, Chieti, Italy Email gallenga@unich.it Patients treated with intravitreal triamcinolone acetonide The paper by Kocabora and coworkers (2008) underlines the message that patients treated with intravitreal triamcinolone acetonide are at risk of increased intraocular pressure (IOP) even after the clearance period o...

Correspondence: Pier Enrico Gallenga University Eye Clinic, G.D’Annunzio University, Chieti, Italy Email gallenga@unich.it Patients treated with intravitreal triamcinolone acetonide The paper by Kocabora and coworkers (2008) underlines the message that patients treated with intravitreal triamcinolone acetonide are at risk of increased intraocular pressure (IOP) even after the clearance period o...

OBJECTIVE To compare the effect of intravitreal triamcinolone acetonide with focal/grid photocoagulation on the progression of diabetic retinopathy. METHODS We performed an exploratory analysis of participants with diabetic macular edema randomly assigned to receive laser therapy or intravitreal triamcinolone acetonide (1 or 4 mg). Fundus photographs were obtained at baseline and 1, 2, and 3 ...

Ophthalmic drug delivery to the posterior segment of eye has been challenging due complex ocular anatomy. Intravitreal injection drugs was introduced deliver therapeutic doses in segment. Different diseases including age-related macular degeneration, diabetic edema, retinal vein occlusions, uveitis, and cystoid among others, have historically treated with intravitreal corticosteroids injections...

1. Danis RP, Ciulla TA, Pratt LM, Anliker W. Intravitreal triamcinolone acetonide in exudative age-related macular degeneration. Retina. 2000;20:244-250. 2. Martidis A, Duker JS, Greenberg PB, et al. Intravitreal triamcinolone for refractory diabetic macular edema. Ophthalmology. 2002;109:920927. 3. Park CH, Jaffe GJ, Fekrat S. Intravitreal triamcinolone acetonide in eyes with cystoid macular e...

PURPOSE To compare the effect of early versus late intravitreal injection of triamcinolone in patients with macular edema due to branch retinal vein occlusion (BRVO). METHODS Twenty eyes of 20 patients with macular edema from BRVO, including 10 with duration after onset of or <or= 3 months and 10 with duration of 3 months, were treated using a single intravitreal triamcinolone injection (4 mg...

BACKGROUND To quantitatively compare short-term hard exudates (HEs) alteration in patients with diabetic macular edema (DME) after intravitreal triamcinolone, dexamethasone implant or bevacizumab injections. METHODS This retrospective study enrolled DME eyes with HEs that underwent a single-dose intravitreal injection of triamcinolone (25 eyes), dexamethasone implant (20 eyes), or three month...

PURPOSE to report a case of severe ocular hypertension occurring as a complication after a single intravitreal injection of triamcinolone acetonide for the treatment of a diabetic cystoid macular edema. METHODS interventional case report. RESULTS a 63-year-old pseudophakic diabetic woman developed a severe and relatively sudden IOP increase to 50 mm Hg one month after receiving a single 4-m...

PURPOSE To evaluate the prophylactic efficacy of selective laser trabeculoplasty for preventing an increase in intraocular pressure (IOP) after intravitreal triamcinolone acetonide injection. DESIGN Prospective, comparative, interventional case series. METHODS We studied 31 eyes with a baseline IOP of 21 mm Hg or more of 31 patients for which intravitreal triamcinolone acetonide injection w...