INTRODUCTION Few studies have evaluated the efficacy of intralesional bleomycin injection combined with electroporation for the treatment of cutaneous tumors. However, the phenomenon that electroporation can enhance the cytotoxicity of bleomycin in vivo by 300-700 fold has been intensely investigated. CASE PRESENTATION Keratoacanthoma in an 86-year-old patient was treated with intralesional b...

Background: Common resistant-to-therapy warts pose a challenge to both clinicians and patients. Among many destructive and immunotherapeutic options, no single, fully effective treatment has been suggested yet. Many investigations, including those using intralesional antigen administrations, have demonstrated that cellular immunity plays a major role in the clearance of human papilloma virus (H...

PURPOSE To investigate the efficacy of intralesional 20% aspirin injection for treatment of experimental peritoneal endometriosis. METHODS Peritoneal endometriosis was experimentally induced in forty adult nulligravid female rabbits. On day 30 post-endometriosis induction, rabbits were randomly divided to assess early (10 days) and late (20 days) effects of intralesional injection of physiolo...

Purpose: Comparison between the effectiveness of intralesional injection of long acting steroid (Triamcinolone acetonide) and surgical management (Incision and Curettage). Method: Hospital-based, two arm, prospective, comparative, interventional studyon 100patients who presented with chalazion who fulfill inclusion and exclusion criteria and gave informed consent were taken for the study. Preop...

Background and aim: Warts are the most common clinical presentation of human papilloma virus infection of human skin and mucosa. They are more common on hand, foot, face and genital area. They are benign skin colour lesions with different clinical forms. There is no specific treatment for them. In this trial the therapeutic effect of intralesional injection of bleomycin and cryotherapy on...

Cutaneous changes after local corticosteroid administration may include dermal atrophy, hyperpigmentation, alopecia, and hypopigmentation. Linear hypopigmentation and atrophy after intralesional injection of triamcinolone acetonide has been reported in the literature as a very rare side effect. A 30-year-old woman visited our dermatology department for a linear hypopigmented patch with atrophy ...

BACKGROUND Tennis elbow is an overuse injury affecting people performing repetitive forearm movements. It is a soft tissue disorder that causes significant disability and pain. The aim of the study was to establish that an intramuscular steroid injection is effective in the short-term pain relief and functional improvement of tennis elbow. The severity of pain at the injection site was monitore...

BACKGROUND Intralesional injection of corticosteroids is an effective treatment for tumors of the head and neck. Complications are rare but include permanent loss of vision. We designed a study to investigate the mechanism for this complication. METHODS Three fellowship-trained pediatric ophthalmologists participated in the study in a nonmasked fashion. Four patients received 5 separate treat...

PURPOSE To investigate periorbital lipogranuloma cases that developed after autologous fat injection and to determine various treatment outcomes from these cases. METHODS This retrospective study involved 27 patients who presented with periocular mass (final diagnosis of lipogranuloma) and had history of facial autologous fat injection. The collected data included information on patient sex, ...

Salivary mucocele is a common lesion derived from minor salivary glands with various surgical or nonsurgical treatment modalities. To evaluate the effect of a highly potent corticosteroid (dexamethasone) in the management of salivary mucocele, we performed intralesional injection of dexamethasone in nine patients with labial mucocele. Complete healing of lesions observed in seven of nine patien...