OBJECTIVE To assess role of some inflammatory mediators in patients with primary and recurrent lumbar disc herniation. Expression of IL-6, transforming growth factor (TGF)-1, insulin-like growth factor (IGF)-1, and Bcl-2-associated X protein (BAX) have been shown to be more intense in the primary group than the recurrent goup, but this mediators may be important aspects prognostic. METHODS 19...

main reasons for workforce losses. Disc herniation is important as it both causes symptoms and requires prolonged treatment. Intervertebral discs are 23 formations existing between adjacent surfaces of the vertebral bodies from the axis to the sacrum.1 The area surrounding the nucleus pulposus consists of fibers, which include a number of chondrocytes. Therefore, the tissue is known as "fibroca...

Tuina manipulation has long been used in the treatment of lumbar intervertebral disc herniation, although its therapeutic mechanisms remain uncertain. The specific characteristic syndrome of this disease is lumbocrural pain in varying degrees, which is due to mechanical compression, aseptic inflammation, blood circulation disturbance and dystrophy. These factors can act on the involved nerve ro...

Background: The purpose of this study was to identify the effects of eight weeks of conventional and suspension corestability exercises by use of the designed device on characteristic of intervertebral discs in low back pain.Methods: A total of 27 men with chronic low back (CLB) pain due to lumbar disc herniation in L4-L5 and L5-S1 regionswere enrolled in this quasi-experiment...

AIM To investigate the risk factors for lumbar intervertebral disc herniation (L4/L5 or L5/S1) severe enough to require surgery of the lower spine among 9 isolated populations of Croatian islands and to evaluate predictive value, sensitivity, and specificity of a simple screening test based on the understanding of the risk factors in this population. METHODS In a sample of 1001 examinees from...

Intervertebral disc herniation of the lumbar spine is a common disease presenting with low back pain and involving nerve root radiculopathy. Some neurological symptoms in the majority of patients frequently improve after a period of conservative treatment. This has been regarded as the result of a decrease of pressure exerted from the herniated disc on neighboring neurostructures and a gradual ...

Many medical image processing techniques rely on accurate shape modeling of anatomical features. The presence of shape abnormalities challenges traditional processing algorithms based on strong morphological priors. In this work, a sparse shape reconstruction from a statistical shape model is presented. It combines the advantages of traditional statistical shape models (defining a 'normal' shap...

Intradural disc herniation is rare. In a colon cancer patient who suffered from low back pain for several years, MRI examination showed evidence of vacuum phenomenon and ring enhancement at the level of L3-4. Intradural herniation of an intervertebral disc was confirmed surgically. Pathological evidence of intradiscal gas is rarely reported in the literature, however, an association between int...

BACKGROUND Previous studies mostly did not separate between symptomatic disc herniation combined with osteochondrosis/spondylosis of the lumbar spine and symptomatic disc herniation in radiographically normal intervertebral spaces. This may at least in part explain the differences in the observed risk patterns. AIMS To investigate the possible aetiological relevance of physical and psychosoci...

Spontaneous regression of a herniated nucleus pulposus (HNP) occurs where intervertebral disc herniation loses its volume partly or totally without surgical interventions. In 1985, Teplick and Haskin first documented the spontaneous resolution of lumbar disc by computerized tomography and they reported that 9 out of their 55 patients harboring lumbar disc herniation showed spontaneous regressio...