Antioxidant phytochemicals are investigated as novel treatments for supportive therapy in beta-thalassemia. The dietary indicaxanthin was assessed for its protective effects on human beta-thalassemic RBCs submitted in vitro to oxidative haemolysis by cumene hydroperoxide. Indicaxanthin at 1.0-10 microM enhanced the resistance to haemolysis dose-dependently. In addition, it prevented lipid and h...

objective: pre-natal diagnosis is the most effected way to prevent genetic diseases in a society. the aim of this research was to show the prevention level of the birth of the children with major thalassemia disorder and the demographic condition of the people referring to the shahid dastgheib genetic center in shiraz for the pre natal diagnosis. materials and methods: the present research was ...

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

Malaventura C, et al. Deferasirox, deferiprone and desferrioxamine treatment in thalassemia major patients: cardiac iron and function comparison determined by quantitative magnetic resonance imaging. Comparison of effects of oral deferiprone and subcutaneous desfer-rioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Effects of chelation therapy on cardiac ...