an improved and facile preparation of 3,7-dinitro-1,3,5,7-tetraazabicyclo [3,3,1] nonane(dpt) has been developed starting from urea. in the procedure dpt was synthesized vian,n’-dinitrourea (dnu) as intermediate and various operating parameters such astemperature, ph and molar ratio of reagents have been optimized to give maximum yield ofthe desired product. the low cost method is concise, oper...

[reaction: see text] We describe the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase Phe445 site-saturated mutants that generate truncated tricyclic and altered deprotonation product profiles. Among these mutants, only polar side-chain group substitutions genetically complemented yeast viability and produced spatially related product diversity, supporting the Johnson model that cation...

Numerous biopharmaceuticals are produced in recombinant microorganisms in the controlled environment of a bioreactor, a process known as Upstream Process. To minimize product loss due to physico-chemical and enzymatic degradation, the Upstream Process should be directly followed by product purification, known as Downstream Process. However, the Downstream Process can be technologically complex ...

Tensor product smooths provide the natural way of representing smooth interaction terms in regression models because they are invariant to the units in which the covariates are measured, hence avoiding the need for arbitrary decisions about relative scaling of variables. They would also be the natural way to represent smooth interactions in mixed regression models, but for the fact that the ten...

This study addresses a capacitated intermediate product selection and blending problem typical for two-stage production systems in the food processing industry. The problem involves the selection of a set of intermediates and end product recipes characterizing how those selected intermediates are blended into end products to minimise the total operational costs under production and storage capa...

In this paper we study a skew product map F with a measure μ of positive entropy. We show that if on the fibers the map are C diffeomorphisms with nonzero Lyapunov exponents, then F has ergodic measures of intermediate entropies. To construct these measures we find a set on which the return map is a skew product with horseshoes along fibers. We can control the average return time and show the m...

denitrification is a reduction of nitrate by heterotrophic and autotrophic bacteria that may ultimately produce molecular nitrogen (n2) through a series of intermediate nitrogen compounds.vermiculite is a hydrous phyllosilicate mineral (mg, fe+2,fe+3)3[(al,si)4o10](oh)2·4h2o with several layers for bacterial immobilization. the goal of this study was removal of nitrate from water with vermiculi...