نتایج جستجو برای: interleukin 23

تعداد نتایج: 280903  

Journal: :Journal of neuroimmunology 2008
Adi Vaknin-Dembinsky Gopal Murugaiyan David A Hafler Anne L Astier Howard L Weiner

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). In MS, myeloid dendritic cells (mDCs) secrete elevated amounts of IL-23, a potent proinflammatory cytokine, compared to healthy donors. Here, we examined the role of CD46, a complement binding factor, in mDCs by analyzing cytokine and chemokine production in healthy donors and patients with MS. There ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی 1393

علیرغم توصیه های فراوان در زمینه انجام کرایوتراپی به دنبال خونریزی های موسکولواسکلتال تحقیقات کمی در این زمینه وجود دارد. همچنین یافته های متناقضی در رابطه با تاثیرکرایوتراپی بر انعقاد خون و التهاب ارائه شده است. بنابراین هدف از این مطالعه بررسی تاثیر کرایوتراپی بر محیط مفصل، دما، تورم فضای بین پتلا و کوندیلهای فمور، اصطکاک مفصل و سیتوکین های التهابی interleukin 1β و tnf- α و سیتوکین ضدالتهابی ...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

Journal: :iranian journal of allergy, asthma and immunology 0
ali mosayebian department of immunology, school of medicine, isfahan university of medical sciences, isfahan, iran. mazdak ganjalikhani-hakemi cellular and molecular immunology research center, faculty of medicine, isfahan university of medical sciences, isfahan, iran. rezvan meshkat department of immunology, faculty of medicine, shahrekord university of medical sciences, shahrekord, iran. ramin ghasemi department of immunology, school of medicine, isfahan university of medical sciences, isfahan, iran. hossain khan-ahmad department of genetics and molecular biology, faculty of medicine, isfahan university of medical sciences, isfahan, iran. morteza samadi department of immunology, faculty of medicine, shahid sadoughi university of medical sciences, yazd, iran and reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, iran.

the snp (rs11209026, arg381gln, r381q) in the il-23 receptor (il23r) confers protection against multiple inflammatory diseases, representing one of the most significant human genetic polymorphisms in inflammatory diseases. we, therefore, investigated the association between il-23 r r381q gene polymorphism and asthma.this case-control study was performed on 209 patients, and 200 healthy controls...

2005
Kiyoko S. Akagawa Toshifumi Hibi Akira Hasegawa Nagamu Inoue Noriaki Watanabe Toshiro Sato Katsuyoshi Matsuoka Kumiko Arai Nobuhiko Kamada Tadakazu Hisamatsu Susumu Okamoto Takaaki Nakai

2013
Hongtao Dong Qiuming Li Ying Zhang Wei Tan Zhengxuan Jiang

PURPOSE The interleukin-23 receptor (IL-23R) has been shown to be associated with ankylosing spondylitis (AS) in many different populations. This study examined whether IL-23R polymorphisms were associated with susceptibility to this disease in a Chinese Han population. METHODS Three single-nucleotide polymorphisms (SNP), rs7517847, rs11209032, and rs17375018, were genotyped in 291 AS patient...

2013
Di Hu Guohua Hu Jing Zhu Yang Shen Houyong Kang Suling Hong

OBJECTIVE Polymorphism of the interleukin-23 receptor gene corresponds with susceptibility to several immune-related diseases. For the terminal differentiation of IL-17-producing effector T-helper cells in vivo, the interleukin-23 receptor gene is of vital importance. As shown recently, Th17 cells probably have a great influence on the pathogenesis of allergic airway diseases. Our intention was...

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