While small molecule inhibitors of the bacterial ribosome have been instrumental in understanding protein translation, no such probes exist to study ribosome biogenesis. We screened a diverse chemical collection that included previously approved drugs for compounds that induced cold sensitive growth inhibition in the model bacterium Escherichia coli. Among the most cold sensitive was lamotrigin...

Mitochondrial translation involves a complex interplay of ancient bacteria-like features and host-derived functionalities. Although the basic components of the mitochondrial translation apparatus have been recognized, very few protein factors aiding in recruiting ribosomes on mitochondria-encoded messenger RNA (mRNAs) have been identified in higher plants. In this study, we describe the identif...

background aging often accompanies declines in muscular capabilities that hinder the performance of daily functions. one of the paramount objectives in occupational therapy is preserving clients’ independence through their ability to conduct instrumental daily living activities. objectives the current study aimed to evaluate the validity and reliability of two subscales of the independent livin...

After an introduction which addresses some basic questions, this article is organized around three points: The theoretical framework of the so-called « instrumental approach » which has been a theme in the last

Movie is an art which has aesthetic purpose. It used to be a form of entertainment, but as time goes by, movie can media spread certain messages the public. One those movies from China and language Chinese. Therefore, it necessary have translation Chinese Indonesian, uses subtitle translation. In process translation, shifting found for most time. This research aims find out two problems researc...