Melatonin and gamma-aminobutyric acid (GABA) have been shown to regulate sleep. The nocturnal concentrations of melatonin, GABA and total antioxidants may relate to insomnia in stroke patients. In this prospective single-center non-randomized controlled clinical trial performed in the China Rehabilitation Research Center, we analyzed the relationship of nocturnal concentrations of melatonin, GA...

AIM Little is known about why some patients respond to cognitive behavioral therapy for insomnia, whereas other patients do not. To understand differences in treatment response, there is a dire need to examine processes of change. The purpose was to investigate the long-term association between insomnia-related worry and outcomes following cognitive behavior therapy for insomnia. METHODS Sixt...

This article states that insomnia can or should be defined in physiologic terms; insomnia is better understood from a neurobiological perspective. A review of the neurobiology of sleep and wakefulness is provided with a special emphasis on the implications for insomnia. A complete understanding of insomnia requires the neurobiological characterization of insomnia be informed by modern cognitive...

BACKGROUND To examine the correlates of insomnia disorder with different durations in home-dwelling older adults. METHODS A cross-sectional survey in the Shih-Pai area of Taipei City, Taiwan (The Shih-Pai Sleep Study). A total 4047 subjects over the age of 65 years completed the study (2259 men and 1788 women). The Pittsburgh Sleep Quality Index and the duration of insomnia symptoms were used...

INSOMNIA CAN BE AN ACUTE EXPERIENCE OR A CHRONIC DISORDER, CHARACTERIZED BY DIFFICULTY IN FALLING ASLEEP AND/OR REMAINING ASLEEP or by poor quality of sleep.1 The sleep difficulty is associated with daytime distress, such as tiredness, negative mood, or difficulty with memory or concentration. The estimated prevalence of chronic insomnia in the US is about 10% (about 25 million people), but pre...

Insomnia is highly prevalent in psychiatric disorders, and it has significant implications. This review focuses on insomnia in the context of anxiety disorders. The prevalence of comorbid insomnia in anxiety disorders is addressed and the clinical implications associated with insomnia are discussed as well as when and how to treat this important comorbidity. Just how specifically insomnia relat...

UNLABELLED BACKGROUND Insomnia is a common public health problem and the prevalence and impact of insomnia in primary care attendees is not well documented in the Asian population. OBJECTIVES To determine the prevalence of self-reported insomnia symptoms amongst adult primary care attendees and the association with socio-demographic factors; to ascertain the impact of insomnia on daily fun...

Insomnia is defined as having 2 or more weeks of sleep difficulties, and approximately 9–18% of American adults suffer from the disorder.1-6 The morbidity rate in Korea is similar to that in America, ranging from 10–17%.7 Chronic insomnia is associated with the following symptoms: daytime fatigue, decrease in memory and concentration, negative mood, lower quality of life, higher rates of absenc...

Studies on personality traits and insomnia have remained inconclusive about which traits show the most direct associations with insomnia severity. It has moreover hardly been explored how traits relate to specific characteristics of insomnia. We here used network analysis in a large sample (N = 2089) to obtain an integrated view on the associations of personality traits with both overall insomn...

aim and background: insomnia, one of the prevalent disorders, in many cases is considered as a sign associated with physical and mental disorders. the present study aimed to investigate the effectiveness of cognitive-behavioral group therapy on these symptoms among male prisoners. methods and materials: subjects of this experimental study were 28 male prisoners in central prison of shiraz who w...