BACKGROUND Intraneural injection during nerve-stimulator-guided sciatic block at the popliteal fossa may be a common occurrence. Although intraneural injections have not resulted in clinically detectable neurologic injury in small studies in human subjects, intraneural injections result in postinjection inflammation in animal models. This study used clinical, imaging, and electrophysiologic mea...

Objective: This research aims to explore the clinical curative effect for the treatment peripheral nerve injury growth factor of Mecobalamin combined with nerve. Methods: 150 cases of patients with peripheral nerve injury treated in the hospital in July were selected from 2011 to 2013. Those patients were randomly divided into three groups according to the types of injured nerve and the undergo...

Injury to the peripheral axons of sensory neurons strongly enhances the regeneration of their central axons in the spinal cord. It remains unclear on what molecules that initiate such conditioning effect. Because ATP is released extracellularly by nerve and other tissue injury, we hypothesize that injection of ATP into a peripheral nerve might mimic the stimulatory effect of nerve injury on the...

background: two main muscles studied in the hand for evaluation of median nerve injuries are opponens pollicis (op) and abductor pollicis brevis (apb). however, riché-cannieu communicating branch (rccb) may limit the use of these muscles in electrodiagnosis. this condition is confusing in the case of median nerve injuries. this study was conducted to evaluate the prevalence of rccb.   methods: ...

Key points † Serious complications of peripheral nerve blocks include nerve injury, catheter infection, bleeding, and LAST. † Intraneural injection occurs frequently with nerve stimulator or ultrasound-guided techniques. It is rarely associated with nerve injury. † Lipid emulsion therapy is effective in treating severe LAST. Summary Complications of peripheral nerve blocks are fortunately rare,...

background: two main muscles studied in the hand for evaluation of median nerve injuries are opponens pollicis (op) and abductor pollicis brevis (apb). however, riché-cannieu communicating branch (rccb) may limit the use of these muscles in electrodiagnosis. this condition is confusing in the case of median nerve injuries. this study was conducted to evaluate the prevalence of rccb.   methods: ...

We report a case of iatrogenic sciatic nerve injury caused by pre-operative intraneural injection of local anaesthetic at total hip replacement. To our knowledge, this is unreported in the orthopaedic literature. We consider sacral nerve blockade in patients undergoing total hip replacement to be undesirable and present guidelines for the management of peri-operative sciatic nerve injury.

Delivering gene constructs into the dorsal root ganglia (DRG) is a powerful but challenging therapeutic strategy for sensory disorders affecting the DRG and their peripheral processes. The current delivery methods of direct intra-DRG injection and intrathecal injection have several disadvantages, including potential injury to DRG neurons and low transfection efficiency, respectively. This study...

Objective(s): Crocin is a constituent of saffron and has many biological functions. The present study aimed to investigate the effects of intraperitoneal (IP) injection of crocin on sciatic nerve regeneration in male Wistar rats. Materials and Methods: Fifty-four rats were divided into 9 groups: groups 1-4 (intact + normal saline and intact + crocin at doses of 5, 20 and 80 mg/kg, respectively)...