BACKGROUND Behavior and substance addiction is one of the risk factors for deep vein thrombosis (DVT). The aim of this study investigating the relationship between the different clinical manifestations pattern of DVT with the way, the amount and duration of narcotic drugs in patients admitted to St. Alzahra Hospital in Isfahan, Iran, during 10 years. METHODS In a cross-sectional study we stud...

Treatment of multidrug-resistant tuberculosis (MDR-TB) is challenging because of the high toxicity of second-line drugs and the longer treatment duration required compared with drug-susceptible TB. The efficacy of treatment for MDR-TB is poorer than that for drug-susceptible TB. The selection of drugs in MDR-TB is based on previous treatment history, drug susceptibility results, and TB drug res...

HIV/AIDS Drugs In article 2203198, Garry Laverty and co-workers develop a long-acting injectable drug delivery implant composed of short peptide sequence attached to the zidovudine. Upon injection, this aqueous solution-based formulation rapidly forms drug-releasing hydrogel in response phosphatase enzymes present within skin space. Clinically relevant concentrations zidovudine were delivered r...

Adverse reactions of injectable drugs usually occur at first administration and are closely associated with the dosage and speed of injection. This phenomenon is correlated with the anaphylactoid reaction. However, up to now, study methods based on antigen detection have still not gained wide acceptance and single physiological indicators cannot be utilized to differentiate anaphylactoid reacti...

Adverse drug events, including in-hospital medication errors, are a well-documented world-wide problem. This interdisciplinary team set out to examine the issues related to the labelling of injectable drugs. We sought answers to the following two questions: (1) To what extent do injectable drug labels adhere to existing Canadian design practice recommendations and regulations for labelling and ...

background: high prices and the risk of bacterial resistance are two important reasons for educations of rational use of antibiotics in general physicians (gps). the aim of this study was to determine the effect of workshop on rational use of antibiotics in gps prescriptions. methods: this was a before-after study, which was conducted on 17 attended gps in the workshop. 2040 prescriptions from ...