abstract: essential oils are commonly used to treat minor health problems. in this study the chemical compositions of lavandula officinalis and thymus vulgaris were determined by gas chromatography and mass spectrometry. gc/ms analysis of t. vulgaris resulted in thymol as the major oil component where as methyl sulfony exhibited as the most abundant constituent of l. officinalis. the antibacter...

Background:Melanogenesis begins with the oxidation of L-tyrosine to L-Dopa by tyrosinase. Inhibition of tyrosinase could be effective in treatment of complications such as skin lesions, eczema and melasma. Inhibition of tyrosinase could be effective in treatment of those complications. The aim of this study was to determine inhibitory activity on tyrosinase and antioxidant activity of Ast...

Background:Melanogenesis begins with the oxidation of L-tyrosine to L-Dopa by tyrosinase. Inhibition of tyrosinase could be effective in treatment of complications such as skin lesions, eczema and melasma. Inhibition of tyrosinase could be effective in treatment of those complications. The aim of this study was to determine inhibitory activity on tyrosinase and antioxidant activity of Ast...

In the present work we carried out a phytochemical and biological investigation on three endemic Hypericum species, i.e. Hypericum thymbrifolium, Hypericum spectabile and Hypericum pseudolaeve from Anatolia in order to discover new sources of natural compounds for the treatment of inflammatory and neurodegenerative disorders. HPLC-DAD analysis indicated that two naphthodianthrones (pseudohyperi...

198 Lactic acid bacteria (LAB) were isolated from Iranian milk samples. Almost all isolatedLAB showed inhibitory activity towards E. coli and S. aureus as Gram negative and Grampositive indicators, respectively. No role was observed for hydrogen peroxide in the activity ofall isolated strains while organic acids proved a prominent role in all detected inhibitoryactivities. Within isolated LAB, ...

A quantitative structure-activity relationship (QSAR) study was conducted for the prediction of inhibitory activity of 1-phenyl[2H]-tetrahydro-triazine-3-one analogues as inhibitors of 5-Lipoxygenase. The inhibitory activities of the 1-phenyl[2H]-tetrahydro-triazine-3-one analogues modeled as a function of molecular structures using chemometrics methods such as multiple linear regression (MLR) ...

  Objective(s): Recently we reported that the soybean 15-lipoxygenase (SLO) inhibitory activity of pyrimido[4,5-b][l,4]benzothiazines largely depends on the orientation of sulfur atom of thiazine core towards FeIII-OH in the active site pocket of the enzyme with subsequent oxidation of sulfur to sulfoxide. In this paper the results of a comparative study on the SLO inhibitory activities of the ...

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. The management of the blood glucose level is a critical strategy in the control of diabetes complications. Inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type II disables mellitus. The goal of the present study...

198 lactic acid bacteria (lab) were isolated from iranian milk samples. almost all isolatedlab showed inhibitory activity towards e. coli and s. aureus as gram negative and grampositive indicators, respectively. no role was observed for hydrogen peroxide in the activity ofall isolated strains while organic acids proved a prominent role in all detected inhibitoryactivities. within isolated lab, ...