preparations of platelet concentrates (pcs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (pmps) with high coagulant activity that may change platelet efficacy and safety issues. high shear stress could cause shedding of pmps from the platelet plasma membrane, platelet aggregation, and activation of the co...

background: platelet mps are produced automatically during platelet storage. their size is about 0.1 – 1 µm and have ability for sub- endothelium adhering, strengthen of platelet aggregation and also platelet pre- coagulation. in fact, the release of membrane particles helps to signal to the neighbor cells or to seclude target cells from apoptosis. the purpose of this study is to determine the ...

background  many biomaterials are used during the open sinus lift surgery, beneath the elevated scheniderian membrane and maxillary sinus bony floor but the search for ideal material continues. methods  in the maxillary posterior atrophic ridges with the bone height less than four millimeters the open sinus lift surgery performed. the autologous platelet-rich plasma (prf) was used as the sole g...

Background  Many biomaterials are used during the open sinus lift surgery, beneath the elevated scheniderian membrane and maxillary sinus bony floor but the search for Ideal material continues. Methods  In the maxillary posterior atrophic ridges with the bone height less than four millimeters the open sinus lift surgery performed. The autologous Platelet-rich plasma (PRF) was used as the sol...

To further characterize the molecular mechanisms of platelet function, we have sought to identify some of the proteins that mediate the secretory events of the platelet release reaction. We report that platelets contain the general elements of the membrane transport apparatus: N-ethylmaleimide sensitive fusion protein (NSF), p115/transcytosis-associated protein (p115/TAP), and the soluble NSF a...

When tobacco is smoked, chewed or snuffed, nicotine is absorbed by the lungs or mucous membrane and quickly moved into the bloodstream, where it is circulated throughout the brain. In fact nicotine is highly dangerous to be consumed in any form. The present study was conducted to know the adverse effects of nicotine on the platelet aggregation in cerebral microvessels of mice. Male mice of aver...