نتایج جستجو برای: influenzavirus
تعداد نتایج: 61 فیلتر نتایج به سال:
چکیده ندارد.
Abstract Accumulating evidence supports the high prevalence of co-infections among Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) patients, and their potential to worsen clinical outcome COVID-19. However, there are few data on Southern Hemisphere populations, most studies date have investigated a narrow spectrum viruses using targeted qRT-PCR. Here we assessed respiratory viral S...
1 Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants Hao-Jie Zhu and John S. Markowitz Department of Pharmaceutical and Biomedical Sciences (H.J.Z., J.S.M.), Laboratory of Drug Disposition and Pharmacogenetics (H.J.Z., J.S.M.), Charles P. Darby Children’s Research Institute, Medical University of South Carolina DMD Fast Forward. Publi...
BACKGROUND Safe and effective antiviral agents are needed to prevent infection with influenza A and B virus. Oseltamivir (GS4104), which can be administered orally, is the prodrug of GS4071, a potent and selective inhibitor of influenzavirus neuraminidases. We studied the use of oseltamivir for long-term prophylaxis against influenza in two placebo-controlled, double-blind trials at different U...
BACKGROUND There are, to our knowledge, no prospective studies of respiratory tract infections in human immunodeficiency virus (HIV)-infected adults in the highly active antiretroviral therapy (HAART) era. We performed a surveillance study of outpatients who presented with fever and respiratory symptoms to examine the role of viral pathogens in these patients. METHODS Consecutive patients wit...
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