نتایج جستجو برای: inflammatory cell
تعداد نتایج: 1872768 فیلتر نتایج به سال:
Two-pore domain potassium channels, like KCNK2, are known to play an important role in inflammatory diseases such as multiple sclerosis (MS). Upregulation of cellular adhesion molecules in mouse brain microvascular endothelial cells (MBMECs) of Kcnk2-/- mice resulted in elevated leukocyte trafficking into the central nervous system under inflammatory conditions. The current project aims to gain...
Background: Fumonisins, a family of mycotoxins, are mainly found in wheat, corn and their products. Previous studies have shown that fumonisin B1 (FB1), the most abundant and toxic of known fumonisins, has been associated with many animal and human diseases including cancer. In the present study, the effects of FB1 were examined on the production of inflammatory cytokines in intestine and stoma...
mast cells play an important role in a variety of inflammatory diseases, particularly asthma and atopy. peroxisome proliferator-activated receptor gamma (pparγ) is a member of the large nuclear hormone receptor transcription factor superfamily, and has been recently implicated in the anti-inflammatory response. to investigate a possible role for pparγ in human mast cells, we studied the ...
results aβ (1-42) stimulated the production of the proinflammatory cytokines il6, il1β, tnfα, and il18 in both the primary microglia cell culture and the b92 cell line. both the raav-il4 construct and the ril-4 protein were found to inhibit production of the most important aβ (1-42)-induced proinflammatory cytokine mrnas in the two types of cells with different patterns. conclusions it seems th...
Background and Aim: Rose Bengal is a water-soluble, anionic xanthin dye. It has been used as a safe compound for many years. But, anti-inflammatory effect of Rose Bengal has not been studied. The aim of this study was to determine the effect of Rose Bengal on nitric oxide production and its inflammatory induced response and inducible nitric oxide synthase expression in LPS-activated J774A.1 mac...
Introduction & Objective: Because of widespread use of Functional Endoscopic Sinus Surgery (FESS) technique and basic role of coronal CT- Scan in understanding of normal drainage route of Para-nasal sinuses, identifying the major patterns of inflammatory sinonasal disease and accompanied anatomical variations is crucial for appropriate preoperative surgical planning. The purpose of this stu...
Bisphosphonates are currently used in metabolic disorder of bone however, there have been few studies that reviewed the role of anti-inflammatory and immune modulatory effect of this agent in in-vivo. Bisphosphonates were divided in two classes regarding the structure and mechanism, including amino and non-amino bisphosphonates. The effect of bisphosphonates on cytokine related to in-vitro wa...
The human amniotic membrane known as the innermost single epithelial-covered layer provides many applications such as applicable anti-inflammatory and anti-cancer effects. These immunomodulatory effects belongs to the epithelial cells, a type of epiblast-derived fetal stem cells which currently used for regenerative medicine and transplantation. These cells are collected by author-prepared faci...
Abstract Background and Objectives Recently, mesenchymal stem cells have attracted much attention in regenerative medicine and cell-based therapies. Mesenchymal stem cells are used in regenerative medicine mainly based on their capacity to differentiate into several cell lineages, low immunogenicity, and in particular their anti-inflammatory and immunosuppressive-immunomodulatory properties. ...
Rheumatoid Arthritis (RA) is a chronic, systemic auto-inflammatory disease that targets peripheral joints causing bone erosion, worsened mobility, and lower quality of life. RA complex autoimmune develops through the combined actions many cell types. In particular, monocytes, fibroblasts, T cells play critical roles within arthritic joint driving pathogenesis. These communicate with each other ...
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