ulcerative colitis (uc) and crohn's disease (cd) are chronic inflammatory bowel diseases with uncertain etiology thought to be triggered by interactions between various environmental, genetic and immunologic factors. incidence rate of cd and uc is different in various geographic areas around the world, between 0.1-11 and 0.5-24.5 per 100,000 people for cd and uc, respectively. recent studies in...

crohn's disease is a type of chronic inflammatory bowel disease (ibd) of unknown etiology that may affect any part of the gastrointestinal tract from mouth to anus and shows extra-intestinal involvement. it characteristically shows skip lesions. this case report reported in 2014 describes a middle age pakistani male known to have documented evidence of significant crohn's disease since past 18 ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: symptoms consistent with irritable bowel syndrome (ibs) are common among patients with inflammatory bowel disease (ibd) in remission phase, and clinicians have difficulties in interpreting such symptoms as an ongoing disease activity or a coexistent ibs. we investigated if the assessment of fecal calprotectin (...

ascites in the course of crohn's diseases is rare and is usually a sign of a concomitant malignancy, infection or thrombosis of portal or hepatic vein. herein, we reported on a 26-year-old man who was initially admitted with severe crohn's ileocolitis complicated by copious exudative ascites, abdominal pain and sever diarrhea. in our patient, we could not find any of the aforementioned conditio...

background: minimal bright red bleeding per rectum (mbrbpr) is a common complaint in adult patients. most studies have not been performed in patients with strictly minimal brbpr, and there are no evidence-based recommendations for this group of patients. materials and methods: patients with complaints as small amounts of red blood after wiping or a few drops of blood in the toilet bowl after de...

background: evidence has shown a link between allergic disease and inflammatory bowel diseases (ibds). we investigated food allergy in iranian pediatric ibd patients. materials and methods: a cross-sectional study was conducted on a consecutive sample of children with newly  diagnosed ibd referring to mofid children’s university hospital in tehran (iran) between november 2013 and march 2015.dat...

crohn’s disease (cd) is rarely presented with lower gi bleeding (lgib) which eludes the clinician. a 25-year-old lady with severe rectorrhagia was presented with no history of constipation, diarrhea or abdominal pain. colonoscopy revealed ulcers in the rectum, sigmoid colon, and terminal ileum. crohn’s pathologic features were detected in the terminal ileum. the bleeding was controlled via supp...

inflammatory bowel diseases (ibd) were systemic disorders involving many organ systems. besides intestinal manifestations, extra intestinal manifestations (eims) including neurologic complications have been reported among 6%-40% of ibd patients. ulcerative colitis (uc) was a subtype of ibd only affecting the colonic mucosa and sub mucosa. although the eims of uc could affect any organ system, c...

background : ulcerative colitis an inflammatory bowel disease (ibd) and chronically idiopathic immune related that associates with extraintestinal manifestations such as arthritis. despite of the highly specificity ofanti-cyclic citrullinated peptide (ccp) antibodies for rheumatoid arthritis, their role in ibd remains unclear . there are only a few studies on the prevalence of anti-ccp antibodi...

objectives: iron chelators, such as maltol and kojic acid, have antioxidant and anti-inflammatory properties. they may have beneficial effects on inflammatory bowel disease (ibd) because iron can develop and aggravate inflammation in ibd. in the present study, the effect of selected iron chelators and anti-oxidants were evaluated on a model of trinitrobenzene sulfonic acid (tnbs)-induced coliti...