background: acute blood purification (abp) therapy is used regularly in the clinical setting and reportedly alleviates organ failure associated with severe systemic inflammatory responses, leading to reduced mortality. the present study aimed to determine whether there is a difference in efficacy between polysulfone (ps) membranes, which are currently used regularly in the clinical setting, and...

background: the expanse of dendritic cells (dc) differentiation plays an important role in determining immune response. dc-based immunosuppressive drugs have notable side effects in increasing the risk of infectious diseases and cancers. g2013, as a novel anti-inflammatory and immunosuppressive agent, has been tested in experimental model of multiple sclerosis. the aim of this study was to cond...

statement of problem: despite the wide range of new dental materials, there is still a need for biomaterials demonstrating high biocompatibility, antimicrobial effects and ideal mechanical properties. purpose: the aim of this study was to histologically evaluate the pulpal response to a conventional glass ionomer, a resin modified glass ionomer and a calcium hydroxide in human teeth. materials ...

urtica dioica is a perennial plant used as herbal medicine due to its many pharmacological and clinical effects. because of its antioxidant activity, it is widely used in traditional diabetes treatment but is also known as antimicrobial, anti inflammatory or anti prostate cancer agent. extensive studies have been conducted on different parts of this plant and their biological effects. here we r...

epilepsy is a neurological disease of the central nervous system. it is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. in the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...

introduction: black pepper (piper nigrum l.) is one of the medicinal plants being used to prevent and manage stroke in persian medicine. current findings support its anti-inflammatory, radical scavenging and neuroprotective characteristics. in this study, we aimed to evaluate role of black pepper on functional and histopathological outcomes of stroke in an animal model of mcao. materials and me...

systemic amyloidosis is a very rare complication of inflammatory bowel disease (ibd). the reported cases of secondary amyloidosis in children with ibd are much fewer than those reported in adults. herein, a teenage boy with crohn’s disease is presented who developed nephrotic syndrome due to renal involvement secondary to amyloidosis, whereas the patient was under treatment with corticosteroid ...

chronic inflammatory demyelinating polyneuropathy is an autoimmune disease with progressive and relapsing courses. the main clinical presentations are diffuse deep tendon hyporeflexia or areflexia and symmetric proximal-distal muscles weakness. myasthenia gravis is also an immune mediated disease with fluctuating ocular and bulbar symptoms and sometimes weakness. although both myasthenia gravis...

fruits of olea europaea l. have been used for centuries in folk medicine to treat many inflammatory diseases. in order to evaluate the anti-nociceptive activities of the methanolic and aqueous extracts of defatted fruits of o. europaea, formalin test was used and for evaluation of anti-inflammatory effects of the extract, the volume of paw edema was measured. the results revealed that both extr...

gastric inflammatory myofibroblastic tumor (imt) is a rare tumor with and unpredictable prognosis usually find in young adults. we present an 18-year-old man with gastric imt. he complained of epigastric pain, intermittent fever and night sweating associated with weight loss since two years ago. physical examination showed anemic and cachestic features with mild abdominal tenderness in palpitat...