Abstract This article re-reads Lyric VII of the poem Advent , dialogue Mary and Joseph. The division speeches in this lyric has been debated, largely on grounds plausibility emotions that are apparently expressed by characters, but there fact clear pragmatic for seeing only three poem. emotional expression these should not be seen terms character psychology, rather establishment negotiation rel...

Statins inhibit hepatic 3-hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) reductase with consequent suppression of cholesterol biosynthesis. The advent of these drugs has significantly impacted the treatment of cardiovascular disease with well documented benefit in primary and secondary prevention1-3. However, several clinical and basic science investigations suggested that the beneficial effects...

Biosimilars represent a new class of medicinal products that will have significant impact on clinical use. They are identical on an amino acid sequence level to existing reference biopharmaceutical products (originals). However, they may exhibit differences on a protein level. This paper provides a brief overview of biosimilar development and describes the risk and challenges that should be con...