objective: to evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (nlr), platelet to lymphocyte ratio (plr) and red blood cell distribution width (rdw) to platelet ratio (rpr)) can be used as reliable markers for the diagnosis of premature ovarian insufficiency (poi) and to determine if there is a relationship between these markers and follicle stimulating hormone (fs...

background: thiamine (vitb1) is a vitamin with various important physiological functions and postulated therapeutic effects.  its use as an analgesic in neuropathic pain has been undergoing in clinical settings. however, there has been little experimental investigation on this effect. in this study, anti-nociceptive and anti-inflammatory effects of thiamine were investigated in mice. methods: t...

bell`s palsy is explained as a sudden paralysis/paresis of all muscle groups on one side of the face due to inflammation of facial nerve, the frequency of bell palsy in diabetic patients is a matter of controversy. there are some reports that refer to bell`s palsy as occurring more commonly in patients with diabetes, or even prediabetes. amosd, korczyn in his studies had shown that a high frequ...

sleep plays a vital role in regulating physiological mechanisms in the human body. nowadays, by the change of lifestyle and as a consequence of longer work hours and increased accessibility to media, sleep disturbance becomes a common problem in modern society. many studies demonstrated that sleep disturbance triggers a systemic low-grade inflammation by increasing the level of several cytokine...

epilepsy is a disorder categorized by recurrent seizures and leads to changes in neuronal death and neurogenesis. recently the search for new targets in the therapy of epilepsy has focused on brain inflammation because brain inflammation and the associate blood brain barrier damage appears to be basic part of epilepsy pathophysiology-erythropoietin (epo) regulates biological processes counting ...

statement of problem: various factors are involved in causing inflammation following root canal treatment. controlling these factors may relieve the related pain. one of these factors is extrusion of debris beyond the apex. although debris extrusion happens in all instrumentation techniques, researchers have declared that in coronal flaring technique, there is minimum debris extrusion. purpose:...

background: soymilk replacement in the diet might have beneficial effects on inflammation and cardiovascular risk factors for non-menopausal overweight and obese female adults. we evaluated the effects of soymilk compared to cow's milk on inflammation and cardiovascular risk factors among overweight and obese female adults. materials and methods: this was a cross-over randomized clinical trial ...

background there is a strong relationship between physical inactivity and low-grade inflammation and its adverse health outcomes, particularly cardiovascular disease. the level of anti-inflammatory and pro-inflammatory cytokines may be changed by exercise. objectives the aim of the present study was to determine the response of certain inflammatory biomarkers to exercise with differences in max...

inflammatory myofibroblastic tumor is an uncommon benign neoplasm and its presentation in small bowel is rare. due to clinical manifestation, laboratory data and radiologic results, there is an increased risk of over diagnosis as malignant tumors particularly malignant lymphoma in childhood therefore may be resulting in wrong therapeutic approach. however pathologic findings could be demonstrat...

abstract background : pain is one of the main protests of inflammatory diseases, hence, understanding the mechanisms which involved in the induction and persistence of pain is essential. microglia is a contributing factor in the onset and maintenance of inflammation. increased microglial   activation increases the level of central pro-inflammatory cytokines and the development of central sensit...