Chronic wound infections are typically polymicrobial; however, most in vivo studies have focused on monospecies infections. This project was designed to develop an in vivo, polymicrobial, biofilm-related, infected wound model in order to study multispecies biofilm dynamics and in relation to wound chronicity. Multispecies biofilms consisting of both Gram negative and Gram positive strains, as w...

a chronic wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time or wounds that do not heal within three months are often considered chronic. chronic wounds often remain in the inflammatory stage for too long and may never heal or may take years. chronic wound patients often report pain as dominant in their lives. persistent pain is the main problem ...

OBJECTIVE To evaluate the results and benefits obtained from the topical use of negative pressure wound therapy (NPWT) in patients with infected wounds. METHODS This was a retrospective study of 20 patients (17 males and three females, mean age 42 years) with infected wounds treated using NPWT. The infected wounds were caused by trauma. The treatment system used was VAC.® (Vacuum Assisted Clo...

Case report. A 14-year-old schoolboy was bitten by an Alsatian dog, sustaining a puncture wound over the dorsal surface ofthe terminal interphalangealjoint of the right little finger. Primary closure of the wound was performed without wound toilet and no antibiotics were given. One week later the wound was infected and flucloxacillin was prescribed. He continued to have considerable pain, swell...

Septic arthritis of the sternoclavicular joint (SCJ) is a rare condition accounting for 0.5% of bone and joint infections. The majority of cases require joint resection and advancement flaps to provide coverage to the resulting wound defect. However, in the setting of an infected wound space, surgeons are often inclined to allow wound healing by secondary intention. Negative pressure wound ther...

Reproducible experimental surgical-wound infections in mice for use in the evaluation of topical antibacterial agents are described. The experimental would was created on the backs of mice by means of a midline incision and was infected by means of cotton sutures monocontaminated with Staphylococcus aureus or Pseudomonas aeruginosa. The course of these wound infections was followed by quantitat...

Vitreous loss: with inadequate Vitrectomy and incarceration of vitreous in the wound. Wound leak: large tunnels, inadequately sutured tunnels or wounds made with blunt, repeatedly used knives and with faulty wound apposition. Prolonged time of surgery Repeated insertions and removal of instruments ? Prolene Haptics of I.O.L. Diabetes Infected instruments: especially canulated ones and improperl...

the microorganisms have been noted as the main cause of delayed wound healing.the most common pathogen causing the wound infections is staphylococcus aureus. silver nanoparticles (agnps) show ample antibacterial activities. in the present study, the effect of agnps on mouse wounds inoculated with s. aureus was investigated. sixty male mice (20 to 30 g) were anesthetized, full-thickness skin wou...

OBJECTIVE To develop and refine qualitative mapping and quantitative analysis techniques to define 'thermal territories' of the post-partum abdomen, the caesarean section site and the infected surgical wound. In addition, to explore women's perspectives on thermal imaging and acceptability as a method for infection screening. METHOD Prospective feasibility study undertaken at a large Universi...