Formation of the vertebrate axis may involve a Wnt signaling cascade similar to the Drosophila wingless pathway. Zebrafish wnt8 is a candidate for involvement in axis specification insofar as it is expressed maternally and when overexpressed it can induce goosecoid, a transcription factor normally expressed in the embryonic shield. In this study we demonstrate that beta-catenin, a cadherin asso...

The organizer in vertebrate embryos has been shown to play a central role in their development by antagonizing ventralizing signals and promoting dorsal development. The ventral homeobox gene, Xvex-1, is capable of fulfilling some of the functions of BMP-4. By fusion to activation and repression domains, Xvex-1 was shown to function as a repressor of transcription. The activator version of Xvex...

The induction of different cell fates along the dorsoventral axis of the Drosophila embryo requires a graded activity of the EGF receptor tyrosine kinase (DER). Here we have identified primary and secondary target genes of DER, which mediate the determination of discrete ventral cell fates. High levels of DER activation in the ventralmost cells trigger expression of the transcription factors en...

We have obtained evidence that a known intracellular component of the cadherin cell-cell adhesion machinery, beta-catenin, contributes to the development of the body axis in the frog Xenopus laevis. Vertebrate beta-catenin is homologous to the Drosophila segment polarity gene product armadillo, and to vertebrate plakoglobin (McCrea, P. D., C. W. Turck, and B. Gumbiner. 1991. Science (Wash. DC)....

We have obtained evidence that a known intracellular component of the cadherin cell-cell adhesion machinery, /3-catenin, contributes to the development of the body axis in the frog Xenopus laevis. Vertebrate/3-catenin is homologus to the Drosophila segment polarity gene product armadillo, and to vertebrate plakoglobin (McCrea, P. D., C. W. Turck, and B. Gumbiner. 1991. Science (Wash. DC). 254: ...

Many control schemes have been proposed for induction motor and permanent magnet synchronous motor control, which are almost highly complex and non-linear. Also, a simple and efficient method for unified control of the electric moto are rarely investigated. In this paper, a novel control method based on rotor flux orientation is proposed. The novelties of proposed method are elimination of q-ax...

in conventional direct torque control (dtc), the stator flux is usually kept constant by controlling the x-axis component of the stator voltage in the stator flux reference frame. the torque is then controlled by the y-axis component of stator voltage. in this scenario, the stator current does not exceed its permissible value. however, in the so-called optimal efficiency mode, the induction mot...