Heparin-induced thrombocytopenia (HIT) is characterized clinically by thrombocytopenia, hypercoagulability, and increased thrombosis risk, serologically platelet-activating anti-platelet factor 4 (PF4)/heparin antibodies. Heparin-“induced” acknowledges that HIT usually triggered a proximate immunizing exposure to heparin. However, certain non-heparin medications (pentosan polysulfate, hypersulf...

SARS-CoV-2 induced lower respiratory tract (LRT) disease can deteriorate to acute distress syndrome (ARDS). Because the release of neutrophil extracellular traps (NETs) is implicated in ARDS pathogenesis, we investigated presence NETs and correlates pathogenesis blood LRT samples critically ill COVID-19 patients. Plasma NET levels peaked early after ICU admission correlated with RNA load sputum...

Introduction: cerebral vein thrombosis is a rare complication of nephrotic syndrome (NS).We report a known case of NS with hemorrhagic thrombosis. Case report: A boy with previous history of NS was admitted with headache and decrease of level of consciousness and his brain images were revealed hemorrhagic thrombosis Conclusions: cerebral vein thrombosis must be considered in patients with...