diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. the objective of the present study was to evaluate the effect of aqueous extract of cydonia oblonga mill. fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. the extract showed anti hyper lipidemic...

background: the present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and gaba at dentate gyrus of streptozotocin-induced diabetic rats. methods: after 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and gaba were investigated. results: the results showed that glutamate levels were significantly decreased in dia...

conclusions troxerutin may reduce the vascular complications and tissue injuries induced by chronic diabetes in rat aorta through increasing the activity of tissue antioxidant system and reducing the level of lipid peroxidation. materials and methods male wistar rats were randomly divided into four groups (n = 8/each): control, control plus troxerutin, diabetic and diabetic plus troxerutin. dia...

Background: The most devastating manifestations of diabetes mellitus are vascular complications. Although there are many factors involved in the pathogenesis of diabetic vasculopathy, many studies suggest a role for glucose–induced oxidative stress. Studies in animal models, have demonstrated that the administration of antioxidants restores normal endothelial functions. The study was designed t...

objective(s): the object of the study is to examine the effects of δ9-tetrahydrocannabinol (thc) against oxidative stress in the blood and excretion of thc metabolites in urine of type 2 diabetic rats. materials and methods: the control (n=8), thc control (n=6), diabetes (n=8) and diabetes + thc (n=7) groups were created. type 2 diabetes was induced by nicotinamide (na, 85 mg/kg) + streptozotoc...

insulin dependent diabetes mellitus (iddm) results from irreversible loss of beta cells (β-cells) of the pancreas. a streptozotocin (stz)-induced diabetes in animal model mimics, in some aspects, recent onset iddm. this study was conducted to investigate the effect of nicotinamide on experimentally-induced iddm. thirty spraque dawley rats were divided into 3 groups; a control group, a diabetic ...