نتایج جستجو برای: indian populations
تعداد نتایج: 302477 فیلتر نتایج به سال:
a total of 1695 blood samples collected from ten ethnically distinct populations of iran (turks and kurds of rezaieh, lurs, aabolis, baluchis, turks and kurds of shrvan, zoroastrians, tehranis, and kermanis) were examined for six polymorphic red cell enzyme systems, namely red cell acid phosphatase (ap), adenylate kinase (ak), phosphoglucomutase (pgm1), esteraxe d (esd), adenosine deaminase (ad...
CONTEXT India is considered a treasure for geneticists and evolutionary biologists due to its vast human diversity, consisting of more than 4500 anthropologically well-defined populations (castes, tribes and religious groups). Each population differs in terms of endogamy, language, culture, physical features, geographic and climatic position and genetic architecture. These factors contributed t...
Prostate cancer (PCa) is the most common non-skin cancer and the second leading cause of cancer death among men in the world. Growth, maintenance and the expression of genes involved in the production of steroids, may alter the susceptibility of prostate cancer. One such gene, CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1) is involved in the activation of many carcinogens and i...
Introduction: Drug transporters are key determinants of pharmacokinetic and pharmacodynamic profiles of certain drugs. SLC47A1 (MATE1) and SLC47A2 (MATE2) are major efflux transporters involved in the hepatic and renal excretion of many cationic drugs including metformin. Our study was proposed to determine the normative frequencies of the single nucleotide polymorphisms (SNPs) rs2289669 and rs...
Understanding the genetic origins and demographic history of Indian populations is important both for questions concerning the early settlement of Eurasia and more recent events, including the appearance of Indo-Aryan languages and settled agriculture in the subcontinent. Although there is general agreement that Indian caste and tribal populations share a common late Pleistocene maternal ancest...
Seven human-specific Alu markers were studied in 574 unrelated individuals from 10 endogamous groups and 2 hill tribes of Tamil Nadu and Kerala states. DNA was isolated, amplified by PCR-SSP, and subjected to agarose gel electrophoresis, and genotypes were assigned for various Alu loci. Average heterozygosity among caste populations was in the range of 0.292-0.468. Among tribes, the average het...
BACKGROUND It has been suggested that ethnicity can make a significant difference to the likelihood of thromboembolic stroke related to atrial fibrillation. Ethnic differences have been shown to alter inflammatory and haemostatic factors; however, this may all be confounded by differences in cardiovascular risk factors between different ethnicity. The impact of different ethnicities on the thro...
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