A great deal of interest has recently focused on conducting inference the parameters in a high-dimensional linear model. In this paper, we consider simple and very naïve two-step procedure for task, which (i) fit lasso model order to obtain subset variables, (ii) least squares lasso-selected set. Conventional statistical wisdom tells us that cannot make use standard tools resulting (such as con...

Stigma and stereotyping of marginalized groups often is insidious and shows up in unlikely places, for instance in how clinical trials consider dropouts in treatment research. A surprising number of studies presume that people who do not complete the study protocol relapse and code their data as if they had been observed. There is no good statistical rationale for this treatment of missing data...

Section 2 of the 1957 Homicide Act is indefensible: the concept of 'mental responsibility' is a hybrid which turns the psychiatrist witness either into a thirteenth juryman or a spare barrister. But reform does not lie along the lines suggested by the Butler Committee or the Criminal Law Revision Committee. The latter leaves the jury with insufficient guidance; the former returns to the bad eig...

The biological complexity of gene expression makes simulation of gene expression data difficult. We propose a spike-in simulation that adds a single simulated gene to the data set of interest. Features of this spike-in gene may be manipulated to observe how often the spiked-in gene appears in the list of differentially expressed genes. This approach provides insight into the data analysis metho...

Praise and blame of managed mental health care are on the rise on many fronts, including allegations that it could adversely affect quality of care, access to care, the physician/patient relationship, and informed patient choice. Given the heterogeneity among managed mental health care organizations--each with differing practices--it is difficult to sift the ethically defensible concerns from t...

In a 2014 paper in Theory and Research in Education, Howard Curzer and colleagues critique the Defining Issues Test of moral judgment development according to eight criteria that are described as difficulties any measure of educational outcomes must address. This article highlights how Curzer et al. do not consult existing empirical evidence, misunderstand the model and method associated with t...

Despite the tremendous accomplishments in science and technology during this century, we go into the next century with nearly one fourth of the world population living in severe poverty and the gap between the rich and the poor widening. How can we alter this utterly indefensible situation? What changes in our development strategy can lead us to a more equitable society? The formidable power of...

There is some intuitive plausibility to the idea that composers create musical works by indicating sonic types in a historical context. But the idea is technically indefensible as it stands, requiring a thorough representational reform that also eliminates the type-theoretic commitments of current versions. On the reformed account, musical 'indication' is an operation of high level representati...